Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 7/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30611256 | 0.86 | DHODH (0.48) | SYKALDH1A1KIF11CYP1A2CYP3A4 | |
| SCHEMBL29110319 | 0.86 | MAPT (0.49) | SYKTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL24596362 | 0.79 | TAS2R14 (0.44) | KDM4ESYKTUBB4ATUBBTUBA3C | |
| SCHEMBL10642215 | 0.78 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1NPC1RAB9A | |
| SCHEMBL2437507 | 0.76 | TUBB4A (0.52) | KDM4ECFTRSYKTUBB4ATUBB | |
| SCHEMBL30649421 | 0.76 | KIF11 (0.48) | KDM4EHSD17B10SYKCTSCKIF11 | |
| SCHEMBL26756689 | 0.76 | KIF11 (0.48) | KDM4EHSD17B10SYKCTSCKIF11 | |
| SCHEMBL3200764 | 0.75 | TUBB4A (0.51) | KDM4EHSD17B10CFTRSYKTUBB4A | |
| SCHEMBL26631663 | 0.75 | KIF11 (0.45) | KDM4EHSD17B10SYKCTSCKIF11 | |
| SCHEMBL29656731 | 0.74 | TUBB4A (0.50) | CFTRSYKTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903613-A | 2-oxo quinazoline five-membered heterocyclic derivative, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-10-20 | — | — | CN | disclosed |