Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | MAT2A | P31153 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30611283 | 1.00 | KIF11 (0.39) | KIF11ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL29110240 | 0.79 | MAT2A (0.38) | ALDH1A1MAPTKDM4EBRD4ADORA1 | |
| SCHEMBL30611257 | 0.79 | MAT2A (0.38) | ALDH1A1MAPTKDM4EBRD4ADORA1 | |
| SCHEMBL30611292 | 0.77 | GRIN2D (0.46) | POLBBRD4ADORA1MAT2AADORA2A | |
| SCHEMBL29110342 | 0.77 | GRIN2D (0.46) | POLBBRD4ADORA1MAT2AADORA2A | |
| SCHEMBL29110326 | 0.72 | MAT2A (0.48) | MAT2A | |
| SCHEMBL30611220 | 0.72 | MAT2A (0.48) | MAT2A | |
| SCHEMBL29569871 | 0.69 | MAT2A (0.49) | ALDH1A1KDM4EMAT2ARECQLPDE4B | |
| SCHEMBL30499843 | 0.68 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EPOLBADORA1 | |
| SCHEMBL2582029 | 0.65 | KDM5A (0.52) | ALDH1A1MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903613-A | 2-oxo quinazoline five-membered heterocyclic derivative, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-10-20 | — | — | CN | disclosed |