Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAT2A | P31153 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30611302 | 1.00 | HTT (0.48) | HTTMAT2AKMT2ALMNAMEN1 | |
| SCHEMBL30611246 | 0.86 | MAT2A (0.47) | HTTMAT2AKMT2ALMNAMEN1 | |
| SCHEMBL29110318 | 0.86 | MAT2A (0.47) | HTTMAT2AKMT2ALMNAMEN1 | |
| SCHEMBL30611321 | 0.84 | HTT (0.51) | HTTMAT2AKMT2ALMNAMEN1 | |
| SCHEMBL29110311 | 0.84 | HTT (0.51) | HTTMAT2AKMT2ALMNAMEN1 | |
| SCHEMBL29110375 | 0.83 | ALDH1A1 (0.49) | HTTMAT2AKMT2ALMNAMEN1 | |
| SCHEMBL30611338 | 0.83 | ALDH1A1 (0.49) | HTTMAT2AKMT2ALMNAMEN1 | |
| SCHEMBL30611262 | 0.82 | MEN1 (0.51) | HTTMAT2AKMT2ALMNAMEN1 | |
| SCHEMBL27388968 | 0.82 | MEN1 (0.51) | HTTMAT2AKMT2ALMNAMEN1 | |
| SCHEMBL11453080 | 0.81 | LMNA (0.65) | HTTKMT2ALMNAMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903613-A | 2-oxo quinazoline five-membered heterocyclic derivative, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-10-20 | — | — | CN | disclosed |