SCHEMBL29110709

SCHEMBL29110709

Oc1c(Br)cccc1Br.[SiH3]O[SiH3]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
TDP1 Q9NUW8 4/20 0.39
CYP3A4 P08684 4/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 6/20 0.36
CA2 P00918 5/20 0.36
LMNA P02545 5/20 0.36
HSD17B10 Q99714 4/20 0.36
HPGD P15428 4/20 0.36
CA1 P00915 3/20 0.36
ALOX15 P16050 3/20 0.36
RECQL P46063 2/20 0.36
CA6 P23280 2/20 0.36
ADAMTS4 O75173 1/20 0.36
EGFR P00533 1/20 0.36
FYN P06241 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
MMP8 P22894 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL416446 0.88
SCHEMBL14840044 0.85 CRHBP (0.46) CRHBPCRHR2TDP1CYP3A4TSHR
SCHEMBL69568 0.74
SCHEMBL11323890 0.74 CA1 (0.45) CRHBPCRHR2TDP1CYP3A4TSHR
SCHEMBL1927956 0.70 ALOX12 (0.64) CYP3A4TSHRALDH1A1CA2LMNA
SCHEMBL10534856 0.70 ALDH1A1 (0.45) CRHBPCRHR2TDP1CYP3A4ALDH1A1
SCHEMBL1423679 0.70
SCHEMBL10672666 0.70
SCHEMBL2018126 0.70
SCHEMBL4576127 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116917039-A Novel carbonylation catalyst and process for preparing the same 诺沃梅尔公司 2023-10-20 CN disclosed