Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29112280 | 0.89 | NQO2 (0.54) | NQO2MTNR1AMTNR1BIDO1MEN1 | |
| SCHEMBL4893405 | 0.86 | NQO2 (0.58) | NQO2MTNR1AMTNR1BIDO1MEN1 | |
| SCHEMBL6925241 | 0.83 | NQO2 (0.56) | NQO2MTNR1AMTNR1BIDO1MEN1 | |
| SCHEMBL28848653 | 0.83 | CA2 (0.56) | NQO2LMNAKMT2ANAMPTSIGMAR1 | |
| SCHEMBL8419482 | 0.82 | MTNR1A (0.67) | NQO2MTNR1AMTNR1BIDO1MEN1 | |
| SCHEMBL21680877 | 0.81 | NQO2 (0.57) | NQO2MTNR1AMTNR1BIDO1MEN1 | |
| SCHEMBL4381773 | 0.81 | NQO2 (0.61) | NQO2MTNR1AMTNR1BIDO1MEN1 | |
| SCHEMBL29112257 | 0.81 | NQO2 (0.49) | NQO2IDO1NAMPTSIGMAR1CA1 | |
| SCHEMBL29682117 | 0.81 | NQO2 (0.49) | NQO2IDO1NAMPTSIGMAR1CA1 | |
| SCHEMBL6874527 | 0.81 | TDP1 (0.59) | NQO2MTNR1AMTNR1BIDO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263493-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | Sanofi (FR) | 2023-10-25 | — | — | EP | disclosed |
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |
| WO-2022133027-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-06-23 | — | — | WO | disclosed |