Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29112414 | 0.92 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL30626433 | 0.92 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL305653 | 0.92 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL29682105 | 0.80 | HSD11B1 (0.33) | EPHX1 | |
| SCHEMBL7978200 | 0.80 | HSD11B1 (0.33) | EPHX1 | |
| SCHEMBL29112277 | 0.80 | HSD11B1 (0.33) | EPHX1 | |
| SCHEMBL6276859 | 0.78 | ALDH1A1 (0.44) | EPHX1 | |
| SCHEMBL9129161 | 0.74 | EPHX1 (0.40) | EPHX1 | |
| SCHEMBL112520 | 0.73 | EPHX1 (0.37) | EPHX1 | |
| SCHEMBL2313131 | 0.72 | EPHX1 (0.39) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556332-B1 | COOLANT SOLUTIONS AND COMPOSITIONS COMPRISING THE SAME | GIVAUDAN SA (CH) | 2016-10-05 | — | — | EP | disclosed |
| US-8093290-B2 | Coolant solutions and compositions comprising the same | GIVAUDAN SA (CH) | 2012-01-10 | — | — | US | disclosed |
| CN-1300095-C | Coolant solutions and compositions comprising the sameitle | GIVAUDAN SA (CH) | 2007-02-14 | — | — | CN | disclosed |
| US-20060051301-A1 | Coolant solutions and compositions comprising the same | GIVAUDAN SA (CH) | 2006-03-09 | — | — | US | disclosed |
| CN-1692096-A | Coolant solutions and compositions containing same | GIVAUDAN SA (CH) | 2005-11-02 | — | — | CN | disclosed |
| EP-1556332-A1 | COOLANT SOLUTIONS AND COMPOSITIONS COMPRISING THE SAME | Givaudan SA (CH) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037764-A1 | COOLANT SOLUTIONS AND COMPOSITIONS COMPRISING THE SAMEITLE | GIVAUDAN SA (CH) | 2004-05-06 | — | — | WO | disclosed |