Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CBR1 | P16152 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24540664 | 1.00 | ESRRG (0.43) | ESRRGTRPV1KDM4EF13A1EPHX2 | |
| SCHEMBL29112444 | 1.00 | ESRRG (0.43) | ESRRGTRPV1KDM4EF13A1EPHX2 | |
| SCHEMBL29112288 | 0.93 | KDM4E (0.45) | ESRRGKDM4EF13A1CYP2D6CYP2C19 | |
| SCHEMBL29112286 | 0.93 | KDM4E (0.45) | ESRRGKDM4EF13A1CYP2D6CYP2C19 | |
| SCHEMBL24540726 | 0.93 | KDM4E (0.45) | ESRRGKDM4EF13A1CYP2D6CYP2C19 | |
| SCHEMBL24540251 | 0.84 | GAA (0.44) | CYP2C19KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24540469 | 0.84 | MEN1 (0.39) | KDM4ECYP2C19KMT2A | |
| SCHEMBL24540521 | 0.84 | ALDH1A1 (0.46) | KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29112470 | 0.84 | GAA (0.44) | CYP2C19KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29112499 | 0.84 | MEN1 (0.39) | KDM4ECYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |