Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153411 | 1.00 | ADRA2A (0.56) | ADRA2AADRA1AAOC3ALDH1A1MAPT | |
| SCHEMBL8619076 | 0.87 | ADRA2A (0.50) | ADRA2AADRA1AAOC3ALDH1A1MAPT | |
| SCHEMBL12714862 | 0.86 | ALDH1A1 (0.52) | AOC3ALDH1A1MAPTSIGMAR1DRD2 | |
| SCHEMBL22620577 | 0.86 | ALDH1A1 (0.52) | AOC3ALDH1A1MAPTSIGMAR1DRD2 | |
| SCHEMBL4582899 | 0.85 | ADRA2A (0.62) | ADRA2AADRA1AALDH1A1NFKB1BLM | |
| SCHEMBL30317544 | 0.85 | ADRA2A (0.62) | ADRA2AADRA1AALDH1A1NFKB1BLM | |
| SCHEMBL7153423 | 0.85 | ADRA2A (0.62) | ADRA2AADRA1AALDH1A1NFKB1BLM | |
| SCHEMBL7783890 | 0.84 | ALDH1A1 (0.48) | AOC3ALDH1A1MAPTSIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL5694882 | 0.83 | AOC3 (0.46) | ADRA2AADRA1AAOC3ALDH1A1MAPT | |
| SCHEMBL13570094 | 0.83 | ALDH1A1 (0.50) | AOC3ALDH1A1MAPTSIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |