Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153423 | 1.00 | ADRA2A (0.62) | ADRA2AADRA1ANFKB1BLMPMP22 | |
| SCHEMBL30317544 | 1.00 | ADRA2A (0.62) | ADRA2AADRA1ANFKB1BLMPMP22 | |
| SCHEMBL28986023 | 0.88 | ADRA2A (0.50) | ADRA2AADRA1ACA1CA2CA12 | |
| SCHEMBL29112412 | 0.85 | ADRA2A (0.56) | ADRA2AADRA1ANFKB1BLMPMP22 | |
| SCHEMBL7145781 | 0.85 | ADRA2A (0.56) | ADRA2AADRA1ANFKB1BLMPMP22 | |
| SCHEMBL7153411 | 0.85 | ADRA2A (0.56) | ADRA2AADRA1ANFKB1BLMPMP22 | |
| SCHEMBL7149112 | 0.84 | ALDH1A1 (0.52) | ADRA2AADRA1ANPSR1L3MBTL1IDO1 | |
| SCHEMBL30988788 | 0.83 | CYP1A2 (0.55) | ADRA2AADRA1ACA1CA2CA12 | |
| SCHEMBL3929054 | 0.83 | LMNA (0.48) | ADRA2AADRA1ACA1CA2CA12 | |
| SCHEMBL21816513 | 0.83 | CYP1A2 (0.55) | ADRA2AADRA1ACA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960032-A | Aryloxy propanol amine beta-adrenaline receptor ligand with beta-arrestin biased agonistic activity and application thereof | 复旦大学 | 2023-04-14 | — | — | CN | disclosed |
| EP-2435019-B1 | DODECA-2E,4E-DIENE AMIDES AND THEIR USE AS MEDICAMENTS AND COSMETICS | WOLFF AUGUST GMBH & CO KG ARZNEIMITTEL DR (DE) | 2015-09-23 | — | — | EP | disclosed |
| CN-101652363-B | Thiazolyl compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2013-04-17 | — | — | CN | disclosed |
| WO-2011105572-A1 | NOVEL HETEROARYL DERIVATIVE | 持田製薬株式会社 (JP) | 2011-09-01 | — | — | WO | disclosed |
| CN-101652363-A | Thiazolyl compounds as kinase inhibitor | SQUIBB BRISTOL MYERS CO US | 2010-02-17 | — | — | CN | disclosed |
| CN-100467598-C | Fungal cell wall synthetic genes | EISAI CO LTD (JP) | 2009-03-11 | — | — | CN | disclosed |
| CN-100467597-C | Fungal cell wall synthetic genes | EISAI CO LTD (JP) | 2009-03-11 | — | — | CN | disclosed |
| CN-101285061-A | Fungal cell wall synthetic genes | EISAI R&D MAN CO LTD (JP) | 2008-10-15 | — | — | CN | disclosed |
| EP-1968568-A2 | INHIBITORS OF Akt ACTIVITY | SmithKline Beecham Corporation (US) | 2008-09-17 | — | — | EP | disclosed |
| CN-101117335-A | Morpholine derivatives for use as dopamine agonists in the treatment of i.a. sexual dysfunction | PFIZER (US) | 2008-02-06 | — | — | CN | disclosed |
| WO-2007076423-A2 | INHIBITORS OF Akt ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| CN-1873003-A | Fungal cell wall synthesis gene | EISAI CO LTD (JP) | 2006-12-06 | — | — | CN | disclosed |
| CN-1873002-A | Fungal cell wall synthesis gene | EISAI CO LTD (JP) | 2006-12-06 | — | — | CN | disclosed |
| CN-1249227-C | Fungal cell wall synthetic genes | EISAI CO LTD (JP) | 2006-04-05 | — | — | CN | disclosed |
| CN-1449443-A | Fungal cell wall synthetic genes | EISAI CO LTD (JP) | 2003-10-15 | — | — | CN | disclosed |
| WO-2001009125-A1 | NOVEL 8-CARBONYL CHROMAN DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |
| CN-1073428-A | Aromatic amino alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic use | SANKYO CO (JP) | 1993-06-23 | — | — | CN | disclosed |
| US-5128369-A | Antiallergens, bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0404197-A2 | Arylalkylamine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |
| EP-0030030-A1 | Derivatives of 2-aminoethanol, processes for their preparation, pharmaceutical compositions containing such compounds and the use the latter | CIBA-GEIGY AG (CH) | 1981-06-10 | — | — | EP | disclosed |