Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30626434 | 1.00 | TSHR (0.39) | TSHRIDO1FFAR1ACMSDHSD11B1 | |
| SCHEMBL2640848 | 0.86 | HSD11B1 (0.43) | TSHRFFAR1ACMSDHSD11B1OPRM1 | |
| SCHEMBL17817788 | 0.82 | TSHR (0.40) | TSHRIDO1FFAR1HSD11B1OPRM1 | |
| SCHEMBL29112397 | 0.81 | GAA (0.46) | CNR2KMT2A | |
| SCHEMBL29682363 | 0.81 | GAA (0.46) | CNR2KMT2A | |
| SCHEMBL16293142 | 0.81 | TSHR (0.54) | TSHRIDO1FFAR1HSD11B1SMN1; SMN2 | |
| SCHEMBL24660952 | 0.81 | TSHR (0.40) | TSHRIDO1FFAR1HSD11B1CYP3A4 | |
| SCHEMBL2674910 | 0.81 | ALDH1A1 (0.41) | TSHRIDO1FFAR1HSD11B1SMN1; SMN2 | |
| SCHEMBL17817801 | 0.79 | NR4A2 (0.50) | FFAR1SMN1; SMN2PKMKMT2A | |
| SCHEMBL21199813 | 0.76 | CHRNA1 (0.45) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |