Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 7/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26699684 | 0.94 | PDE3B (0.45) | PDE3BPDE3ANOTUMKDRFFAR4 | |
| SCHEMBL29113210 | 0.90 | PDE3B (0.46) | PDE3BPDE3ANOTUMKDRS1PR1 | |
| SCHEMBL12649105 | 0.88 | PDE3B (0.47) | PDE3BPDE3ANOTUMKDRHRH3 | |
| SCHEMBL1769918 | 0.84 | PDE3B (0.59) | PDE3BPDE3ANOTUMKDRHRH3 | |
| SCHEMBL13071053 | 0.80 | ALDH1A1 (0.46) | PDE3BPDE3ANOTUM | |
| SCHEMBL13071051 | 0.80 | NOTUM (0.62) | PDE3BPDE3ANOTUMKDRHRH3 | |
| SCHEMBL13071049 | 0.79 | PDE3B (0.59) | PDE3BPDE3ANOTUMKDR | |
| SCHEMBL25698377 | 0.79 | NOTUM (0.47) | PDE3BPDE3ANOTUMKDRHRH3 | |
| SCHEMBL14767785 | 0.79 | PDE3B (0.46) | PDE3BPDE3ANOTUMKDRHRH3 | |
| SCHEMBL12649067 | 0.79 | PDE3B (0.46) | PDE3BPDE3ANOTUMKDRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126231-A | Peptoid STAT protein degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-11-28 | — | — | CN | disclosed |