Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 6/20 | 0.38 |
| ▸ | JAK2 | O60674 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | SCN2B | O60939 | 1/20 | 0.35 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.34 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29113546 | 0.87 | LRRK2 (0.39) | LRRK2JAK1JAK2MAPK1JAK3 | |
| SCHEMBL29929758 | 0.83 | LRRK2 (0.44) | LRRK2CYP1A2JAK1JAK2MAPK1 | |
| SCHEMBL26980380 | 0.83 | LRRK2 (0.44) | LRRK2CYP1A2JAK1JAK2MAPK1 | |
| SCHEMBL29113534 | 0.83 | LRRK2 (0.39) | LRRK2CYP1A2JAK1JAK2MAPK1 | |
| SCHEMBL26979886 | 0.81 | JAK3 (0.52) | JAK3MAPK3 | |
| SCHEMBL29929286 | 0.81 | JAK3 (0.52) | JAK3MAPK3 | |
| SCHEMBL29929752 | 0.80 | CCNT1 (0.41) | LRRK2CYP1A2JAK1JAK2MAPK1 | |
| SCHEMBL26980190 | 0.80 | CCNT1 (0.41) | LRRK2CYP1A2JAK1JAK2MAPK1 | |
| SCHEMBL29113559 | 0.79 | JAK2 (0.49) | JAK2JAK3SYK | |
| SCHEMBL30671851 | 0.79 | JAK2 (0.49) | JAK2JAK3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136184-A | Aminopyrimidine compounds and methods of use thereof | 泰拉生物科学公司 | 2023-11-28 | — | — | CN | disclosed |