Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.49 |
| ▸ | SYK | P43405 | 2/20 | 0.49 |
| ▸ | STAT6 | P42226 | 11/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30671851 | 1.00 | JAK2 (0.49) | JAK2SYKSTAT6FLT3BTK | |
| SCHEMBL26980492 | 0.85 | SYK (0.56) | JAK2SYKJAK3NPC1RAB9A | |
| SCHEMBL29113556 | 0.85 | JAK2 (0.46) | JAK2SYKSTAT6FLT3BTK | |
| SCHEMBL26979838 | 0.85 | BTK (0.56) | JAK2SYKFLT3BTKJAK3 | |
| SCHEMBL26977050 | 0.82 | SYK (0.49) | JAK2SYKJAK3NPC1RAB9A | |
| SCHEMBL29113535 | 0.79 | LRRK2 (0.40) | JAK2SYKJAK3 | |
| SCHEMBL29113546 | 0.79 | LRRK2 (0.39) | JAK2SYKJAK3KCNH2 | |
| SCHEMBL30671844 | 0.79 | JAK2 (0.54) | JAK2SYKSTAT6FLT3BTK | |
| SCHEMBL29113541 | 0.79 | JAK3 (0.40) | JAK2JAK3 | |
| SCHEMBL30931315 | 0.77 | BTK (0.58) | JAK2FLT3BTKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136184-A | Aminopyrimidine compounds and methods of use thereof | 泰拉生物科学公司 | 2023-11-28 | — | — | CN | disclosed |