Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28401900 | 0.85 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14175211 | 0.84 | TDP1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27973172 | 0.81 | KMT2A (0.50) | ALDH1A1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL10914589 | 0.79 | SMN1; SMN2 (0.52) | ALDH1A1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL19354449 | 0.78 | CA12 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28401901 | 0.78 | LMNA (0.45) | KMT2AMEN1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL19409861 | 0.78 | HSD17B1 (0.35) | ALDH1A1SMN1; SMN2MAPK1LMNAMAOA | |
| SCHEMBL2591830 | 0.77 | EPHX2 (0.54) | ALDH1A1KMT2AKDM4EMEN1RAB9A | |
| SCHEMBL11811640 | 0.77 | HSD17B1 (0.53) | KMT2ARAB9AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL27542837 | 0.77 | PDK1 (0.41) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232037-B | Preparation method of benzoyl sulfamoyl-N-substituted benzamide compound | 郑州手性药物研究院有限公司 | 2023-10-27 | — | — | CN | disclosed |