SCHEMBL29113992

SCHEMBL29113992

CCCCCn1cnc(C#N)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 1/20 0.40
CPB2 Q96IY4 3/20 0.39
CPB1 P15086 2/20 0.39
NPC1 O15118 6/20 0.36
RAB9A P51151 6/20 0.36
HTT P42858 6/20 0.36
ALDH1A1 P00352 4/20 0.36
LMNA P02545 3/20 0.36
APOBEC3A P31941 2/20 0.36
APOBEC3G Q9HC16 2/20 0.36
PABPC1 P11940 1/20 0.36
KDM4E B2RXH2 4/20 0.35
POLB P06746 3/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL29192003 0.95 CPB2 (0.43) TBXAS1CPB2CPB1ALDH1A1LMNA
SCHEMBL29192004 0.95 CPB2 (0.43) TBXAS1CPB2CPB1ALDH1A1LMNA
Bromide SCHEMBL29192001 0.93 CPB2 (0.42) TBXAS1CPB2CPB1NPC1RAB9A
SCHEMBL26038699 0.81 CPB2 (0.37) CPB2CPB1KDM4EMAPTCTSL
SCHEMBL24329784 0.80
SCHEMBL23810847 0.77 CPB2 (0.40) TBXAS1CPB2CPB1NPC1RAB9A
SCHEMBL24128290 0.76 TBXAS1 (0.38) TBXAS1CPB2CPB1ALDH1A1LMNA
SCHEMBL26237382 0.74 MEN1 (0.35) TBXAS1
SCHEMBL8591843 0.74 TBXAS1 (0.44) TBXAS1CPB2NPC1RAB9AHTT
SCHEMBL9625860 0.73 TBXAS1 (0.47) TBXAS1CPB2NPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947824-A Monosubstituted 1,2,4, 5-tetrazine compound based on five-membered heterocycle and preparation method thereof 北京大学 2023-10-27 CN disclosed