Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.42 |
| ▸ | CPB1 | P15086 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | GALR3 | O60755 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL29192003 | 0.98 | CPB2 (0.43) | CPB2CPB1CTSLGRK6HSD17B10 | |
| SCHEMBL29192004 | 0.98 | CPB2 (0.43) | CPB2CPB1CTSLGRK6HSD17B10 | |
| SCHEMBL29113992 | 0.93 | TBXAS1 (0.40) | CPB2CPB1CTSLHSD17B10POLB | |
| SCHEMBL23810847 | 0.81 | CPB2 (0.40) | CPB2CPB1POLBTBXAS1ALDH1A1 | |
| SCHEMBL26038699 | 0.81 | CPB2 (0.37) | CPB2CPB1CTSLKMT2AKDM4E | |
| SCHEMBL24329784 | 0.80 | — | — | |
| SCHEMBL24128290 | 0.76 | TBXAS1 (0.38) | CPB2CPB1HSD17B10TBXAS1ALDH1A1 | |
| SCHEMBL26237382 | 0.74 | MEN1 (0.35) | TBXAS1KMT2A | |
| Bromide SCHEMBL16738791 | 0.73 | CPB2 (0.48) | CPB2CPB1POLBTBXAS1ALDH1A1 | |
| SCHEMBL634200 | 0.72 | CYP1A2 (0.45) | CPB2CPB1POLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117583128-A | Zinc combination inhibitor for lead-zinc separation and application thereof | 西北矿冶研究院 | 2024-02-23 | — | — | CN | claimed |
| CN-117583128-A | Zinc combination inhibitor for lead-zinc separation and application thereof | 西北矿冶研究院 | 2024-02-23 | — | — | CN | disclosed |