Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.37 |
| ▸ | FNTB | P49356 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL2911566 | 0.94 | ALDH1A1 (0.33) | FNTAFNTBALDH1A1MAPTSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL2909841 | 0.93 | ALDH1A1 (0.34) | FNTAFNTBALDH1A1MAPTSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL2903756 | 0.86 | GPR119 (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL2912722 | 0.86 | GPR119 (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL2912932 | 0.79 | SMN1; SMN2 (0.47) | FNTAFNTBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2906860 | 0.78 | GSK3A (0.39) | ALDH1A1MAPTSMN1; SMN2LMNAMGLL | |
| SCHEMBL2911739 | 0.78 | CDK1 (0.39) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2909976 | 0.76 | GSK3A (0.39) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2904171 | 0.76 | GSK3A (0.38) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2911578 | 0.76 | GSK3A (0.38) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537099-B1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-11 | — | — | EP | disclosed |