Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.52 |
| ▸ | RARG | P13631 | 7/20 | 0.52 |
| ▸ | RARA | P10276 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053289 | 0.93 | RARB (0.55) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL6572465 | 0.88 | RARA (0.57) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL2911481 | 0.84 | RARG (0.70) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL6433717 | 0.79 | ALOX5 (0.58) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7052829 | 0.78 | RARG (0.70) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL6570341 | 0.74 | RARB (0.55) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7053160 | 0.74 | RARA (0.75) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7047540 | 0.74 | RARB (0.50) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL6535667 | 0.73 | RARG (0.74) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9359800 | 0.70 | RARB (0.52) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255543-B1 | USE OF RETINOID-TYPE COMPOUNDS AS ANTIBACTERIAL AGENTS AGAINST STAPHYLOCOCCUS AUREUS | GALDERMA RES & DEV (FR) | 2010-09-01 | — | — | EP | claimed |