Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | RARA | P10276 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RARG | P13631 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911481 | 0.82 | RARG (0.70) | RARBRARAMEN1KMT2ARARG | |
| SCHEMBL7052829 | 0.82 | RARG (0.70) | RARBRARAMEN1KMT2ARARG | |
| SCHEMBL7053289 | 0.80 | RARB (0.55) | RARBRARAMEN1KMT2ARARG | |
| SCHEMBL2911484 | 0.79 | RARB (0.52) | RARBRARAMEN1KMT2ARARG | |
| SCHEMBL6454889 | 0.79 | RARB (0.70) | ALOX5RARBRARAMEN1KMT2A | |
| SCHEMBL18678069 | 0.77 | RARB (0.65) | ALOX5RARBRARAMEN1KMT2A | |
| SCHEMBL15029021 | 0.75 | ALOX5 (0.51) | ALOX5MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15029156 | 0.74 | KDM4E (0.56) | ALOX5KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13004823 | 0.72 | MEN1 (0.58) | RARBRARAMEN1KMT2ARARG | |
| SCHEMBL29529449 | 0.70 | STS (0.46) | KDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858647-B2 | Retinoid compounds suited for antibacterial applications | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2005-02-22 | — | — | US | disclosed |