SCHEMBL29115686

SCHEMBL29115686

C=COc1c(C=C)cccc1OC

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 8/20 0.45
CYP1A1 P04798 3/20 0.41
CYP1A2 P05177 3/20 0.41
CYP1B1 Q16678 3/20 0.41
PRMT1 Q99873 1/20 0.41
CYP19A1 P11511 1/20 0.41
SRC P12931 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TLR2 O60603 1/20 0.41
ERN1 O75460 1/20 0.41
TLR1 Q15399 1/20 0.41
TLR6 Q9Y2C9 1/20 0.41
MAPT P10636 1/20 0.41
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.40
PDE4B Q07343 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57085 0.86 NFE2L2 (0.58) NFE2L2CYP1A1CYP1A2CYP1B1PRMT1
SCHEMBL25059139 0.86 SMN1; SMN2 (0.48) NFE2L2CYP1A1CYP1A2CYP1B1PRMT1
SCHEMBL8741684 0.81 NFE2L2 (0.47) NFE2L2CYP1A1CYP1A2CYP1B1PRMT1
SCHEMBL16954031 0.79 GSK3A (0.52) NFE2L2CYP1A1CYP1A2CYP1B1PRMT1
SCHEMBL6365322 0.79 NFE2L2 (0.44) NFE2L2CYP1A1CYP1A2CYP1B1PRMT1
SCHEMBL16951902 0.78 CA1 (0.45) NFE2L2CYP1A1CYP1A2CYP1B1PRMT1
SCHEMBL28625833 0.77 ALDH1A1 (0.34) CYP1A2KDM4EHSD17B10LMNAHPGD
SCHEMBL7990624 0.76 TLR2 (0.46) NFE2L2CYP1A1CYP1A2CYP1B1KDM4E
SCHEMBL17417579 0.76 KDM4E (0.54) NFE2L2CYP1A1CYP1A2SRCKDM4E
SCHEMBL14909 0.76 NFE2L2 (0.55) NFE2L2CYP1A1CYP1A2CYP1B1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069918-B Modified acrylic resin and preparation method thereof 广东嘉元新材料有限公司 2024-04-26 CN claimed
CN-117069918-A Modified acrylic resin and preparation method thereof 广东嘉元新材料有限公司 2023-11-17 CN claimed
CN-117069918-B Modified acrylic resin and preparation method thereof 广东嘉元新材料有限公司 2024-04-26 CN disclosed
CN-117069918-A Modified acrylic resin and preparation method thereof 广东嘉元新材料有限公司 2023-11-17 CN disclosed