SCHEMBL28625833

SCHEMBL28625833

C=COc1c(C)cccc1C=C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
TSHR P16473 3/20 0.34
SCN4A P35499 7/20 0.32
CYP1A2 P05177 3/20 0.32
LMNA P02545 2/20 0.32
SCN1A P35498 2/20 0.32
SCN5A Q14524 2/20 0.32
SCN9A Q15858 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 2/20 0.32
NFKB1 P19838 2/20 0.32
CYP2C9 P11712 1/20 0.32
KCNK3 O14649 1/20 0.32
CACNA1F O60840 1/20 0.32
KCNK2 O95069 1/20 0.32
GBA1 P04062 1/20 0.32
MAOA P21397 1/20 0.32
HTR2A P28223 1/20 0.32
SLC6A4 P31645 1/20 0.32
HTR2B P41595 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17063020 0.85 SCN4A (0.38) ALDH1A1TSHRSCN4ACYP1A2LMNA
SCHEMBL5435773 0.83 ALDH1A1 (0.37) ALDH1A1TSHRSCN4ACYP1A2LMNA
SCHEMBL2047299 0.82 CA1 (0.40) ALDH1A1TSHRSCN4ACYP1A2LMNA
SCHEMBL5611771 0.78 SCN4A (0.33) ALDH1A1TSHRSCN4ACYP1A2LMNA
SCHEMBL9317525 0.77 CYP2D6 (0.33) ALDH1A1TSHRSCN4ACYP1A2LMNA
SCHEMBL22476163 0.77 SCN4A (0.38) ALDH1A1TSHRSCN4ACYP1A2LMNA
SCHEMBL16956478 0.77 SCN4A (0.38) ALDH1A1TSHRSCN4ACYP1A2LMNA
SCHEMBL29115686 0.77 NFE2L2 (0.45) CYP1A2LMNAKDM4EHPGDHSD17B10
SCHEMBL16952711 0.76 SCN8A (0.37) ALDH1A1TSHRSCN4ACYP1A2LMNA
SCHEMBL3916235 0.74 KDM4E (0.56) ALDH1A1LMNACYP3A4TP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372494-A Anticoagulation polymer coating material and preparation method thereof 河南驼人医疗器械研究院有限公司 2021-09-10 CN disclosed