SCHEMBL29115698

SCHEMBL29115698

CCOC(=O)C=Cc1cccc(-c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c1C#N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
CYP3A4 P08684 2/20 0.39
NR1H4 Q96RI1 3/20 0.39
ESR1 P03372 1/20 0.39
CCNC P24863 1/20 0.38
CDK8 P49336 1/20 0.38
TTR P02766 1/20 0.38
DPP4 P27487 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
MDM2 Q00987 1/20 0.37
ALOX5 P09917 1/20 0.36
AKT1 P31749 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39303 0.82 ALDH1A1 (0.48) HSD17B1HSD17B2CYP3A4NR1H4CCNC
SCHEMBL39304 0.82 ALDH1A1 (0.48) HSD17B1HSD17B2CYP3A4NR1H4CCNC
SCHEMBL11353236 0.75 L3MBTL1 (0.49) HSD17B1HSD17B2NR1H4TTRDPP4
SCHEMBL11353238 0.75 L3MBTL1 (0.49) HSD17B1HSD17B2NR1H4TTRDPP4
SCHEMBL20515307 0.74 CA12 (0.43) HSD17B1HSD17B2CYP3A4ESR1CCNC
SCHEMBL27645680 0.74 CA12 (0.43) HSD17B1HSD17B2CYP3A4ESR1CCNC
SCHEMBL990905 0.73 ALOX5 (0.41) CA12CA7CA9CA14LMNA
SCHEMBL31505085 0.72 CA12 (0.49) HSD17B1HSD17B2CYP3A4ESR1CCNC
SCHEMBL6910749 0.72 CYP3A4 (0.61) CYP3A4ESR1TTRDPP4CA12
SCHEMBL6910750 0.72 CYP3A4 (0.61) CYP3A4ESR1TTRDPP4CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069612-A Novel method for synthesizing cyanoacrylate 上海应用技术大学 2023-11-17 CN disclosed