Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 5/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29733229 | 0.88 | TYMS (0.45) | TYMSTHRBTHRAHSD17B10HPGD | |
| SCHEMBL18600610 | 0.86 | TYMS (0.44) | TYMSTHRBTHRAESR1ESR2 | |
| SCHEMBL1508109 | 0.85 | TYMS (0.56) | TYMSTHRBTHRAESR1ESR2 | |
| SCHEMBL30342255 | 0.85 | TYMS (0.56) | TYMSTHRBTHRAESR1ESR2 | |
| SCHEMBL3841280 | 0.82 | THRB (0.56) | TYMSTHRBTHRAESR1ESR2 | |
| SCHEMBL29413361 | 0.82 | THRB (0.56) | TYMSTHRBTHRAESR1ESR2 | |
| SCHEMBL9771679 | 0.82 | TYMS (0.49) | TYMSTHRBTHRAESR1ESR2 | |
| SCHEMBL68437 | 0.82 | ALDH1A1 (0.56) | TYMSTHRBTHRAESR1ESR2 | |
| SCHEMBL29374139 | 0.82 | ALDH1A1 (0.56) | TYMSTHRBTHRAESR1ESR2 | |
| SCHEMBL31155341 | 0.81 | TYMS (0.47) | TYMSTHRBTHRAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981758-A | Thermally responsive brush polymers having a copolymer backbone and copolymer arms | 英菲诺姆国际有限公司 | 2023-10-31 | — | — | CN | disclosed |