Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3874382 | 0.98 | CA2 (0.44) | CA2CAMK2AAKR1B1LMNAGAA | |
| SCHEMBL833000 | 0.83 | HIF1A (0.43) | CA2HIF1AHRH3 | |
| SCHEMBL2912607 | 0.79 | CHKA (0.53) | CA2CAMK2AAKR1B1LMNAGAA | |
| Bromide SCHEMBL3874747 | 0.78 | CHKA (0.55) | CA2CAMK2AAKR1B1LMNAGAA | |
| SCHEMBL840566 | 0.77 | HIF1A (0.59) | HIF1A | |
| Water SCHEMBL16037174 | 0.76 | HIF1A (0.57) | HIF1A | |
| SCHEMBL2911826 | 0.72 | MAPT (0.42) | CA2CAMK2AAKR1B1LMNAGAA | |
| SCHEMBL13714805 | 0.72 | LMNA (0.43) | LMNAALDH1A1HPGDMAPT | |
| SCHEMBL69614 | 0.72 | CA2 (0.79) | CA2CAMK2AAKR1B1LMNAGAA | |
| Bromide SCHEMBL3874702 | 0.71 | MAPT (0.41) | CA2CAMK2AAKR1B1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517892-B1 | RING-SUBSTITUTED DIPHENYL AZETIDINONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND USE THEREOF | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-1517892-A1 | RING-SUBSTITUTED DIPHENYL AZETIDINONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND USE THEREOF | Aventis Pharma Deutschland GmbH (DE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000804-A1 | RING-SUBSTITUTED DIPHENYL AZETIDINONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND USE THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-12-31 | — | — | WO | disclosed |