Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515025 | 0.89 | CA4 (0.43) | ALDH1A1MMP1MMP2MMP13PPARG | |
| Acetic Acid SCHEMBL28684431 | 0.80 | PPARG (0.42) | ALDH1A1KMT2AMAPTPPARGL3MBTL1 | |
| SCHEMBL27564325 | 0.79 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTPPARGL3MBTL1 | |
| SCHEMBL11275737 | 0.79 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTPPARGL3MBTL1 | |
| Acetic Acid SCHEMBL29103732 | 0.77 | EPHX2 (0.50) | KMT2ACYP2C19CYP1A2NPC1RAB9A | |
| SCHEMBL13072375 | 0.77 | PPARA (0.50) | ALDH1A1KMT2AMAPTPPARGL3MBTL1 | |
| SCHEMBL11513547 | 0.77 | L3MBTL1 (0.42) | ALDH1A1KMT2AMAPTPPARGL3MBTL1 | |
| SCHEMBL10577288 | 0.76 | PPARG (0.42) | ALDH1A1KMT2AMAPTPPARGL3MBTL1 | |
| SCHEMBL29211960 | 0.76 | CA1 (0.41) | ALDH1A1MMP1MMP2MMP13KMT2A | |
| SCHEMBL12987433 | 0.76 | AKR1C3 (0.56) | KMT2APPARGNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117778115-A | In-situ cleaning composition and in-situ cleaning method for silicon-containing substrate | 昂士特科技(深圳)有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117511413-A | Chemical mechanical polishing composition for metal alloy and polishing method thereof | 昂士特科技(深圳)有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-116254059-B | Chemical mechanical polishing composition for edge polishing | 昂士特科技(深圳)有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-115926629-B | Chemical mechanical polishing composition with improved recycling properties | 昂士特科技(深圳)有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-116814168-A | Chemical mechanical polishing composition and method for silicon-based materials | 昂士特科技(深圳)有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116254059-A | Chemical mechanical polishing composition for edge polishing | 昂士特科技(深圳)有限公司 | 2023-06-13 | — | — | CN | disclosed |