Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
| ▸ | STK10 | O94804 | 1/20 | 0.52 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29120695 | 0.86 | NPC1 (0.61) | IGF1RSTK10SLKNPC1RAB9A | |
| SCHEMBL8674402 | 0.82 | NPC1 (0.52) | STK10SLKNPC1RAB9AMAPT | |
| SCHEMBL29120686 | 0.81 | ALDH1A1 (0.59) | STK10SLKNPC1RAB9AMAPT | |
| SCHEMBL8668406 | 0.80 | NPC1 (0.52) | STK10SLKNPC1RAB9AMAPT | |
| SCHEMBL7354053 | 0.79 | PLK1 (0.50) | STK10SLKNPC1RAB9AMAPT | |
| SCHEMBL29120687 | 0.79 | ALDH1A1 (0.53) | STK10SLKNPC1RAB9AMAPT | |
| SCHEMBL28243562 | 0.76 | NPC1 (0.66) | IGF1RSTK10SLKNPC1RAB9A | |
| SCHEMBL29120689 | 0.76 | BRAF (0.47) | STK10SLKNPC1RAB9AMAPT | |
| SCHEMBL29120693 | 0.75 | SYK (0.54) | STK10SLKNPC1MAPTPOLB | |
| SCHEMBL8669622 | 0.75 | PLK1 (0.61) | SLKAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947756-B | Cyclobutene diketo quinoline compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2025-02-07 | — | — | CN | disclosed |
| WO-2025025472-A1 | CYCLOBUTENEDIONE-BASED QUINOLINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 中国药科大学 | 2025-02-06 | — | — | WO | disclosed |
| CN-116947756-A | Cyclobutene diketo quinoline compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-10-27 | — | — | CN | disclosed |