Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | BRAF | P15056 | 2/20 | 0.52 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 6/20 | 0.47 |
| ▸ | FLT1 | P17948 | 3/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29120786 | 0.88 | FLT1 (0.60) | MEN1KMT2AKDRFLT1LMNA | |
| SCHEMBL29170580 | 0.87 | TRPV4 (0.51) | SMN1; SMN2MEN1KMT2ATRPV4HDAC6 | |
| SCHEMBL29120796 | 0.87 | TRPV4 (0.49) | SMN1; SMN2MEN1KMT2ABRAFTRPV4 | |
| SCHEMBL30620614 | 0.87 | KMT2A (0.49) | SMN1; SMN2MEN1KMT2ATRPV4HDAC6 | |
| SCHEMBL29120815 | 0.87 | KMT2A (0.49) | SMN1; SMN2MEN1KMT2ATRPV4HDAC6 | |
| SCHEMBL29120791 | 0.84 | GRM4 (0.50) | TRPV4GRM4HTTMAPT | |
| SCHEMBL29120804 | 0.84 | MAPT (0.63) | SMN1; SMN2MEN1KMT2ABRAFTRPV4 | |
| SCHEMBL29120805 | 0.84 | TRPV4 (0.47) | MEN1KMT2ABRAFTRPV4GRM4 | |
| SCHEMBL29120793 | 0.83 | MAPT (0.51) | SMN1; SMN2MEN1KMT2ATRPV4POLB | |
| SCHEMBL29120792 | 0.83 | TP53 (0.63) | SMN1; SMN2MEN1KMT2ATRPV4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947822-B | Pyridine biimidazole dimer compound, and preparation method and application thereof | 河南牧业经济学院 | 2024-01-26 | — | — | CN | disclosed |
| CN-116947822-A | Pyridine biimidazole dimer compound, and preparation method and application thereof | 河南牧业经济学院 | 2023-10-27 | — | — | CN | disclosed |