Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30620614 | 1.00 | KMT2A (0.49) | KMT2ASMN1; SMN2PKMTRPV4KCNK3 | |
| SCHEMBL29170597 | 0.88 | LMNA (0.54) | SMN1; SMN2TRPV4MAPTRAB9ANPC1 | |
| SCHEMBL29120798 | 0.87 | SMN1; SMN2 (0.54) | KMT2ASMN1; SMN2TRPV4MAPTRAB9A | |
| SCHEMBL29120796 | 0.87 | TRPV4 (0.49) | KMT2ASMN1; SMN2TRPV4MAPTRAB9A | |
| SCHEMBL29170580 | 0.87 | TRPV4 (0.51) | KMT2ASMN1; SMN2TRPV4MAPTRAB9A | |
| SCHEMBL29120804 | 0.86 | MAPT (0.63) | KMT2ASMN1; SMN2PKMTRPV4MAPT | |
| SCHEMBL29120803 | 0.86 | RAB9A (0.52) | KMT2ASMN1; SMN2TRPV4MAPTRAB9A | |
| SCHEMBL29120791 | 0.84 | GRM4 (0.50) | TRPV4MAPTHTTGSK3BALDH1A1 | |
| SCHEMBL29120805 | 0.84 | TRPV4 (0.47) | KMT2ATRPV4MAPTRAB9ANPC1 | |
| SCHEMBL29120793 | 0.83 | MAPT (0.51) | KMT2ASMN1; SMN2PKMTRPV4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947822-B | Pyridine biimidazole dimer compound, and preparation method and application thereof | 河南牧业经济学院 | 2024-01-26 | — | — | CN | disclosed |
| CN-116947822-A | Pyridine biimidazole dimer compound, and preparation method and application thereof | 河南牧业经济学院 | 2023-10-27 | — | — | CN | disclosed |