Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29120789 | 0.89 | CYP3A4 (0.51) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL29120815 | 0.86 | KMT2A (0.49) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30620614 | 0.86 | KMT2A (0.49) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL29170580 | 0.84 | TRPV4 (0.51) | MAPTMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL29120798 | 0.84 | SMN1; SMN2 (0.54) | MAPTLMNAMEN1KMT2AHPGD | |
| SCHEMBL29120796 | 0.84 | TRPV4 (0.49) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL29120805 | 0.82 | TRPV4 (0.47) | MAPTLMNAMEN1KMT2ABRAF | |
| SCHEMBL29120791 | 0.82 | GRM4 (0.50) | MAPTALDH1A1TP53GRM4HTT | |
| SCHEMBL29170597 | 0.81 | LMNA (0.54) | MAPTALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL29120810 | 0.81 | HDAC6 (0.53) | MAPTLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947822-B | Pyridine biimidazole dimer compound, and preparation method and application thereof | 河南牧业经济学院 | 2024-01-26 | — | — | CN | disclosed |
| CN-116947822-A | Pyridine biimidazole dimer compound, and preparation method and application thereof | 河南牧业经济学院 | 2023-10-27 | — | — | CN | disclosed |