Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100765 | 0.71 | HPGDS (0.46) | HPGDSLTA4H | |
| SCHEMBL104745 | 0.71 | — | — | |
| SCHEMBL440423 | 0.68 | NOTUM (0.42) | — | |
| SCHEMBL27594120 | 0.68 | CYP1A2 (0.40) | HPGDSLTA4H | |
| SCHEMBL912864 | 0.67 | LTA4H (0.37) | HPGDSLTA4H | |
| SCHEMBL13484017 | 0.65 | ENPP3 (0.44) | HPGDSLTA4H | |
| SCHEMBL970056 | 0.65 | KMT2A (0.37) | HPGDSLTA4H | |
| SCHEMBL12571337 | 0.65 | HPGDS (0.41) | HPGDSLTA4H | |
| SCHEMBL28395750 | 0.65 | LTA4H (0.36) | HPGDSLTA4H | |
| SCHEMBL28465840 | 0.65 | HPGDS (0.37) | HPGDSLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104125773-A | N-arylamidine substituted trifluoroethyl sulfide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AG | 2014-10-29 | — | — | CN | claimed |
| CN-103130775-A | Indolinone derivatives serving as tyrosine kinase inhibitors | SHANDONG HENRY MEDICAL TECHNOLOGY CO LTD | 2013-06-05 | — | — | CN | claimed |
| CN-103068811-A | Anthracene [2,3-b:7,6-b' ] dithiophene derivatives and their use as organic semiconductors | MERCK PATENT GMBH | 2013-04-24 | — | — | CN | claimed |
| CN-102947299-A | Alkaloid aminoester derivatives and pharmaceutical compositions thereof | CHIESI FARMA SPA | 2013-02-27 | — | — | CN | claimed |
| CN-102883718-A | Analogues for the treatment or prevention of flavivirus infections | VERTEX PHARMA | 2013-01-16 | — | — | CN | claimed |
| CN-102869657-A | Analogues for the treatment or prevention of flavivirus infections | VERTEX PHARMA | 2013-01-09 | — | — | CN | claimed |
| US-8097644-B2 | Indole compounds having sphingosine-1-phosphate (S1P) receptor antagonist | ALLERGAN, INC. (US) | 2012-01-17 | — | — | US | claimed |
| EP-2262497-A2 | S1P3 RECEPTOR INHIBITORS FOR TREATING INFLAMMATION | Allergan, Inc. (US) | 2010-12-22 | — | — | EP | claimed |
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | claimed |
| CN-101627024-A | ALDH-2 inhibitors in the treatment of addiction | CV THERAPEUTICS INC | 2010-01-13 | — | — | CN | claimed |
| US-20070191313-A1 | INDOLE-3-CARBOXYLIC ACID AMIDE, ESTER, THIOAMIDE AND THIOL ESTER COMPOUNDS BEARING ARYL OR HETEROARYL GROUPS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR ANTAGONIST BIOLOGICAL ACTIVITY | ALLERGAN, INC. | 2007-08-16 | — | — | US | claimed |
| CN-1791838-A | Photoresist composition for deep UV and imaging process thereof | AZ ELECTRONIC MATERIALS USA (US) | 2006-06-21 | — | — | CN | claimed |
| CN-1777414-A | Glycinamide derivative for inhibiting HIV replication | TRIPEP AB (SE) | 2006-05-24 | — | — | CN | claimed |
| CN-1230715-C | Photoresist composition for deep ultraviolet and method thereof | CLARIANT FINANCE BVI LTD (JP) | 2005-12-07 | — | — | CN | claimed |
| CN-1443315-A | Photoresist composition for deep UV and process thereof | CLARIANT FINANCE BVI LTD (VG) | 2003-09-17 | — | — | CN | claimed |
| EP-0646007-B1 | NEW DELTA-17 AND DELTA-20 OLEFINIC AND SATURATED 17$g(b)-SUBSTITUTED-4-AZA-5$g(a)-ANDROSTAN-3-ONES AS 5$g(a)-REDUCTASE INHIBITORS | MERCK & CO INC (US) | 1997-08-13 | — | — | EP | claimed |
| EP-0646007-A4 | — | — | 1995-04-26 | — | — | EP | claimed |
| EP-0646007-A1 | NEW DELTA-17 AND DELTA-20 OLEFINIC AND SATURATED 17-g(b)-SUBSTITUTED-4-AZA-5-g(a)-ANDROSTAN-3-ONES AS 5-g(a)-REDUCTASE INHIBITORS. | MERCK & CO INC (US) | 1995-04-05 | — | — | EP | claimed |
| WO-1993023050-A1 | NEW DELTA-17 AND DELTA-20 OLEFINIC AND SATURATED 17β-SUBSTITUTED-4-AZA-5α-ANDROSTAN-3-ONES AS 5α-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |
| EP-0167651-B1 | PROCESS FOR PRODUCING 3-CEPHEM-4-CARBOXYLIC ACID DERIVATIVES SUBSTITUTED IN 3-POSITION | Antibioticos, S.A. (ES) | 1989-09-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191313-A1 | INDOLE-3-CARBOXYLIC ACID AMIDE, ESTER, THIOAMIDE AND THIOL ESTER COMPOUNDS BEARING ARYL OR HETEROARYL GROUPS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR ANTAGONIST BIOLOGICAL ACTIVITY | S1PR3, S1PR1, S1PR2 | HPGDS 975/4885LTA4H 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.