Sulfuric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	PI4KA	P42356	1/20	0.32

▸	PI4K2B	Q8TCG2	1/20	0.32

▸	PI4K2A	Q9BTU6	1/20	0.32

▸	PI4KB	Q9UBF8	1/20	0.32

▸	ALDH1A1	P00352	3/20	0.32

▸	POLB	P06746	1/20	0.32

▸	HIF1A	Q16665	1/20	0.32

▸	KDM4E	B2RXH2	2/20	0.31

▸	GAA	P10253	2/20	0.31

▸	MEN1	O00255	1/20	0.31

▸	MAPT	P10636	1/20	0.31

▸	PKM	P14618	1/20	0.31

▸	RAB9A	P51151	1/20	0.31

▸	KMT2A	Q03164	1/20	0.31

▸	CYP3A4	P08684	1/20	0.31

▸	THRB	P10828	1/20	0.31

▸	HPGD	P15428	1/20	0.31

▸	ALOX15	P16050	1/20	0.31

▸	TSHR	P16473	1/20	0.31

▸	CASP1	P29466	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Sulfuric Acid SCHEMBL8922217	0.98	PI4KA (0.32)	PI4KAPI4K2BPI4K2API4KBALDH1A1
Sulfuric Acid SCHEMBL9787480	0.89	KDM4E (0.31)	KDM4E
SCHEMBL33843	0.87	—	—
Sulfuric Acid SCHEMBL9325261	0.79	SMPD3 (0.33)	PI4KAPI4K2BPI4K2API4KBALDH1A1
Sulfuric Acid SCHEMBL4599030	0.77	KDM4E (0.31)	ALDH1A1KDM4EGAAMEN1MAPT
Sulfuric Acid SCHEMBL143343	0.73	—	—
Sulfuric Acid SCHEMBL2854050	0.73	CYP1A2 (0.36)	—
SCHEMBL3162681	0.72	PI4KA (0.34)	PI4KAPI4K2BPI4K2API4KB
Sulfuric Acid SCHEMBL5493743	0.72	—	—
Sulfuric Acid SCHEMBL8919999	0.72	CYP1A2 (0.35)	MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1556389-B9	CEPHEM COMPOUNDS	ASTELLAS PHARMA INC (JP)	2015-09-09	—	—	EP	disclosed
EP-1556389-B3	CEPHEM COMPOUNDS	ASTELLAS PHARMA INC (JP)	2015-04-01	—	—	EP	disclosed
EP-1531784-B1	PEARLY-LUSTRE COLORING AGENTS FOR KERATIN FIBERS	PROCTER & GAMBLE (US)	2010-09-08	—	—	EP	disclosed
EP-1663245-B1	CEPHEM COMPOUNDS	ASTELLAS PHARMA INC (JP)	2010-04-07	—	—	EP	disclosed
EP-1556389-B1	CEPHEM COMPOUNDS	ASTELLAS PHARMA INC (JP)	2007-07-25	—	—	EP	disclosed
US-7192943-B2	Cephem compounds	ASTELLAS PHARMA INC. (JP)	2007-03-20	—	—	US	disclosed
US-20070037786-A1	Cephem compounds	WAKUNAGA PHARMACEUTICAL CO., LTD. (JP)	2007-02-15	—	—	US	disclosed
US-7129232-B2	For therapy of of infectious diseases	ASTELLAS PHARMA INC. (JP)	2006-10-31	—	—	US	disclosed
EP-1663245-A1	CEPHEM COMPOUNDS	Astellas Pharma Inc. (JP)	2006-06-07	—	—	EP	disclosed
EP-1166749-B1	Composition and process for dyeing keratinic fibres	WELLA AG (DE)	2005-10-12	—	—	EP	disclosed
EP-1556389-A1	CEPHEM COMPOUNDS	Astellas Pharma Inc. (JP)	2005-07-27	—	—	EP	disclosed
EP-1531784-A1	PEARLY-LUSTRE COLORING AGENTS FOR KERATIN FIBERS	Wella Aktiengesellschaft (DE)	2005-05-25	—	—	EP	disclosed
US-20050096306-A1	Cephem compounds	FUJISAWA PHARMACEUTICAL CO. LTD. (JP)	2005-05-05	—	—	US	disclosed
US-20050081311-A1	Pearly-lustre coloring agents for keratin fibers	WELLA AKTIENGESELLSCHAFT (DE)	2005-04-21	—	—	US	disclosed
WO-2005027909-A1	CEPHEM COMPOUNDS	ASTELLAS PHARMA INC. (JP)	2005-03-31	—	—	WO	disclosed
US-20040132994-A1	Cephem compounds	FUJISAWA PHARMACEUTICAL CO., LTD (JP)	2004-07-08	—	—	US	disclosed
WO-2004039814-A1	CEPHEM COMPOUNDS	ASTELLAS PHARMA INC. (JP)	2004-05-13	—	—	WO	disclosed
WO-2004019895-A1	PEARLY-LUSTRE COLORING AGENTS FOR KERATIN FIBERS	WELLA AKTIENGESELLSCHAFT (DE)	2004-03-11	—	—	WO	disclosed
EP-1166749-A2	Composition and process for dyeing keratinic fibres	Wella Aktiengesellschaft (DE)	2002-01-02	—	—	EP	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20070037786-A1	Cephem compounds	CEP170, ABCB11, SLC7A1	PI4KA 4548/4885PI4K2B 4462/4885PI4K2A 4507/4885
US-20040132994-A1	Cephem compounds	CEP170, ABCB11, RCC2	PI4KA 4214/4885PI4K2B 3915/4885PI4K2A 4009/4885
US-20050096306-A1	Cephem compounds	CEP170, ASS1, C1S	PI4KA 4701/4885PI4K2B 4733/4885PI4K2A 4708/4885
US-20050081311-A1	Pearly-lustre coloring agents for keratin fibers	KRT18, AKR7A2, ELOVL5	PI4KA 3058/4885PI4K2B 3055/4885PI4K2A 2557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.