Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24664167 | 1.00 | MAPK1 (0.42) | MAPK1SCN9AHDAC1HDAC6HDAC5 | |
| SCHEMBL30006191 | 0.91 | SCN9A (0.47) | SCN9AHDAC6MAPTLMNAFFAR1 | |
| SCHEMBL29123609 | 0.91 | SCN9A (0.47) | SCN9AHDAC6MAPTLMNAFFAR1 | |
| SCHEMBL29123537 | 0.90 | MAPK1 (0.42) | MAPK1SCN9AHDAC1HDAC6HDAC5 | |
| SCHEMBL24665367 | 0.89 | LTA4H (0.38) | MAPTFFAR1 | |
| SCHEMBL30006150 | 0.89 | LTA4H (0.38) | MAPTFFAR1 | |
| SCHEMBL24665373 | 0.89 | LTA4H (0.38) | SCN9AHDAC1HDAC6HDAC5MAPT | |
| SCHEMBL30005383 | 0.89 | LTA4H (0.38) | SCN9AHDAC1HDAC6HDAC5MAPT | |
| SCHEMBL24664168 | 0.86 | SCN9A (0.43) | MAPK1SCN9AHDAC1HDAC6HDAC5 | |
| SCHEMBL24665399 | 0.85 | LTA4H (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |