Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | GRN | P28799 | 2/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27171409 | 0.91 | LMNA (0.46) | SCN9AFFAR1GRNSORT1PTPN1 | |
| SCHEMBL27204662 | 0.91 | LMNA (0.46) | SCN9AFFAR1GRNSORT1PTPN1 | |
| SCHEMBL24664168 | 0.91 | SCN9A (0.43) | MAPK1SCN9AGAAFFAR1HDAC1 | |
| SCHEMBL29123536 | 0.90 | MAPK1 (0.42) | MAPK1SCN9AGAAFFAR1HDAC1 | |
| SCHEMBL24664167 | 0.90 | MAPK1 (0.42) | MAPK1SCN9AGAAFFAR1HDAC1 | |
| SCHEMBL29123472 | 0.89 | GRN (0.42) | MAPK1SCN9AFFAR1GRNSORT1 | |
| SCHEMBL27204693 | 0.89 | GRN (0.42) | SCN9AFFAR1GRNSORT1PTPN1 | |
| SCHEMBL27171436 | 0.89 | GRN (0.42) | SCN9AFFAR1GRNSORT1PTPN1 | |
| SCHEMBL29123526 | 0.89 | PTPN1 (0.42) | SCN9AFFAR1GRNSORT1PTPN1 | |
| SCHEMBL29123439 | 0.84 | LTA4H (0.53) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |