Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.74 |
| ▸ | BACE1 | P56817 | 3/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.74 |
| ▸ | MMP9 | P14780 | 3/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.74 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.74 |
| ▸ | MAOA | P21397 | 2/20 | 0.74 |
| ▸ | MAOB | P27338 | 2/20 | 0.74 |
| ▸ | TOP2A | P11388 | 2/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.74 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.74 |
| ▸ | STAT3 | P40763 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31498024 | 1.00 | APP (0.74) | APPMAPTBACE1NFKB1MMP9 | |
| Ammonia Solution, Strong SCHEMBL28303751 | 0.98 | APP (0.74) | APPMAPTBACE1NFKB1MMP9 | |
| Curcumin SCHEMBL28117506 | 0.94 | APP (0.84) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL1378809 | 0.91 | APP (0.80) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL30663618 | 0.90 | APP (0.86) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL8965197 | 0.90 | TOP2A (0.77) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL8965200 | 0.90 | TOP2A (0.77) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL2840285 | 0.88 | HTR1A (0.82) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL2840282 | 0.88 | HTR1A (0.82) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL30240113 | 0.88 | HTR1A (0.82) | APPMAPTBACE1NFKB1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116963724-A | Treatment for human malignant pleural effusion | 萨恩帕斯药物有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116963724-A | Treatment for human malignant pleural effusion | 萨恩帕斯药物有限公司 | 2023-10-27 | — | — | CN | disclosed |