Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.82 |
| ▸ | APP | P05067 | 5/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.72 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | MAOB | P27338 | 3/20 | 0.72 |
| ▸ | BACE1 | P56817 | 3/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | TOP2A | P11388 | 2/20 | 0.72 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.72 |
| ▸ | MAOA | P21397 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.72 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.72 |
| ▸ | STAT3 | P40763 | 2/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.72 |
| ▸ | RELA | Q04206 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2840282 | 1.00 | HTR1A (0.82) | HTR1AAPPCYP2D6ALOX5MAPT | |
| SCHEMBL20668211 | 1.00 | HTR1A (0.82) | HTR1AAPPCYP2D6ALOX5MAPT | |
| SCHEMBL30240113 | 1.00 | HTR1A (0.82) | HTR1AAPPCYP2D6ALOX5MAPT | |
| SCHEMBL27927798 | 0.95 | HTR1A (0.77) | HTR1AAPPCYP2D6ALOX5MAPT | |
| Curcumin SCHEMBL28117506 | 0.93 | APP (0.84) | HTR1AAPPCYP2D6ALOX5MAPT | |
| Curcumin SCHEMBL25240986 | 0.92 | HTR1A (0.73) | HTR1AAPPCYP2D6ALOX5MAPT | |
| Curcumin SCHEMBL25245838 | 0.92 | HTR1A (0.73) | HTR1AAPPCYP2D6ALOX5MAPT | |
| Curcumin SCHEMBL25247326 | 0.92 | HTR1A (0.73) | HTR1AAPPCYP2D6ALOX5MAPT | |
| Curcumin SCHEMBL25287577 | 0.92 | HTR1A (0.73) | HTR1AAPPCYP2D6ALOX5MAPT | |
| Curcumin SCHEMBL25285963 | 0.92 | HTR1A (0.73) | HTR1AAPPCYP2D6ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11964935-B2 | Gingerol derivative having inhibitory activity against biofilm formation and pharmaceutical composition comprising same as effective ingredient for preventing or treating biofilm-caused infection symptom | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) | 2024-04-23 | — | — | US | disclosed |
| CN-112457192-B | Synthetic method of paradol | 桂林理工大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-112457192-A | Synthetic method of paradol | 桂林理工大学 | 2021-03-09 | — | — | CN | disclosed |
| US-20200283364-A1 | GINGEROL DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST BIOFILM FORMATION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING BIOFILM-CAUSED INFECTION SYMPTOM | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) | 2020-09-10 | — | — | US | disclosed |
| EP-2488257-B1 | FORMULATION WITH IRRITATION REDUCING ACTION COMPRISING BISABOLOL AND [6]-PARADOL | SYMRISE AG (DE) | 2018-05-02 | — | — | EP | disclosed |
| US-9549911-B2 | Ginger metabolites and uses thereof | NORTH CAROLINA A&T STATE UNIVERSITY (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160235697-A1 | GINGER METABOLITES AND USES THEREOF | NORTH CAROLINA A&T STATE UNIVERSITY (US) | 2016-08-18 | — | — | US | disclosed |
| US-9272994-B1 | Ginger metabolites and uses thereof | NORTH CAROLINA A&T STATE UNIVERSITY (US) | 2016-03-01 | — | — | US | disclosed |
| US-8951507-B2 | Formulation with irritation reducing action comprising bisabolol and [6]-paradol | SYMRISE AG (DE) | 2015-02-10 | — | — | US | disclosed |
| US-20120258058-A1 | FORMULATION WITH IRRITATION REDUCING ACTION COMPRISING BISABOLOL AND [6]-PARADOL | SYMRISE AG (DE) | 2012-10-11 | — | — | US | disclosed |
| EP-2488257-A2 | FORMULATION WITH IRRITATION REDUCING ACTION COMPRISING BISABOLOL AND [6]-PARADOL | Symrise AG (DE) | 2012-08-22 | — | — | EP | disclosed |
| WO-2010000877-A2 | FORMULATION WITH IRRITATION REDUCING ACTION COMPRISING BISABOLOL AND [6]-PARADOL | SYMRISE GMBH & CO. KG (DE) | 2010-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120258058-A1 | FORMULATION WITH IRRITATION REDUCING ACTION COMPRISING BISABOLOL AND [6]-PARADOL | FHIT, DAGLA, TRPV1 | HTR1A 116/4885APP 1202/4885CYP2D6 83/4885 |
| US-20160235697-A1 | GINGER METABOLITES AND USES THEREOF | GNMT, GSTM2, GSTM1 | HTR1A 2873/4885APP 2419/4885CYP2D6 577/4885 |
| US-20200283364-A1 | GINGEROL DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST BIOFILM FORMATION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING BIOFILM-CAUSED INFECTION SYMPTOM | LSS, F2R, CFTR | HTR1A 1415/4885APP 1017/4885CYP2D6 1825/4885 |
| US-11964935-B2 | Gingerol derivative having inhibitory activity against biofilm formation and pharmaceutical composition comprising same as effective ingredient for preventing or treating biofilm-caused infection symptom | LSS, F2R, CFTR | HTR1A 1415/4885APP 1017/4885CYP2D6 1825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.