Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37563 | 0.85 | KMT2A (0.42) | CYP1A2RAB9AKDM4EL3MBTL1 | |
| Water SCHEMBL28123763 | 0.83 | KMT2A (0.41) | CYP1A2RAB9AKDM4EL3MBTL1 | |
| Bromide SCHEMBL28947954 | 0.83 | KMT2A (0.41) | CYP1A2RAB9AKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11060859 | 0.83 | KMT2A (0.41) | CYP1A2RAB9AKDM4EL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL5694238 | 0.81 | CHRNA7 (0.44) | CYP1A2LMNACYP2C9LDHATP53 | |
| SCHEMBL4063789 | 0.81 | AKT1 (0.43) | LMNARAB9ASMN1; SMN2GABRA1GABRG2 | |
| Water SCHEMBL28124252 | 0.81 | KMT2A (0.39) | CYP1A2RAB9AKDM4EL3MBTL1 | |
| Water SCHEMBL28124251 | 0.81 | KMT2A (0.39) | CYP1A2RAB9AKDM4EL3MBTL1 | |
| Isopropyl Alcohol SCHEMBL27548121 | 0.79 | RAB9A (0.38) | RAB9ASMN1; SMN2LDHATP53ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL5694233 | 0.76 | PTPN1 (0.39) | CYP1A2LMNARAB9ASMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920916-B | Continuous synthesis method of poly (butylene succinate) | 上海师范大学 | 2023-11-28 | — | — | CN | claimed |
| CN-114920916-A | Continuous synthesis method of poly (butylene succinate) | 上海师范大学 | 2022-08-19 | — | — | CN | claimed |
| CN-114920916-B | Continuous synthesis method of poly (butylene succinate) | 上海师范大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-114920916-A | Continuous synthesis method of poly (butylene succinate) | 上海师范大学 | 2022-08-19 | — | — | CN | disclosed |