Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37563 | 0.96 | KMT2A (0.42) | AKT1AKT2RAB9AKMT2AMEN1 | |
| Water SCHEMBL28123763 | 0.93 | KMT2A (0.41) | AKT1AKT2RAB9AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11060859 | 0.93 | KMT2A (0.41) | AKT1AKT2RAB9AKMT2AMEN1 | |
| Bromide SCHEMBL28947954 | 0.93 | KMT2A (0.41) | AKT1AKT2RAB9AKMT2AMEN1 | |
| Water SCHEMBL28124252 | 0.91 | KMT2A (0.39) | AKT1AKT2RAB9AKMT2AMEN1 | |
| Water SCHEMBL28124251 | 0.91 | KMT2A (0.39) | AKT1AKT2RAB9AKMT2AMEN1 | |
| SCHEMBL20054187 | 0.91 | AKT1 (0.30) | AKT1AKT2 | |
| SCHEMBL14564388 | 0.86 | KMO (0.44) | AKT1AKT2RAB9ANPC1SMN1; SMN2 | |
| Isopropyl Alcohol SCHEMBL27548121 | 0.84 | RAB9A (0.38) | AKT1AKT2RAB9AKMT2AMEN1 | |
| Succinic Acid SCHEMBL29123713 | 0.81 | FFAR1 (0.43) | RAB9ASMN1; SMN2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240268216-A1 | TETRADENTATE PLATINUM AND PALLADIUM COMPLEX EMITTERS CONTAINING PHENYL-PYRAZOLE AND ITS ANALOGUES | UNIV ARIZONA STATE (US) | 2024-08-08 | — | — | US | disclosed |
| US-11930698-B2 | Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2024-03-12 | — | — | US | disclosed |
| US-20230115701-A1 | TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES | UNIV ARIZONA STATE (US) | 2023-04-13 | — | — | US | disclosed |
| US-20210111355-A1 | Tetradentate Platinum And Palladium Complex Emitters Containing Phenyl-Pyrazole And Its Analogues | UNIV ARIZONA STATE (US) | 2021-04-15 | — | — | US | disclosed |
| US-20210111355-A1 | Tetradentate Platinum And Palladium Complex Emitters Containing Phenyl-Pyrazole And Its Analogues | UNIV ARIZONA STATE (US) | 2021-04-15 | — | — | US | disclosed |
| US-10937976-B2 | Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-03-02 | — | — | US | disclosed |
| US-10937976-B2 | Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-03-02 | — | — | US | disclosed |
| US-20210024559-A1 | TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES | UNIV ARIZONA STATE (US) | 2021-01-28 | — | — | US | disclosed |
| US-10836785-B2 | Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190013485-A1 | Tetradentate Platinum And Palladium Complex Emitters Containing Phenyl-Pyrazole And Its Analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2019-01-10 | — | — | US | disclosed |
| US-20030018046-A1 | Chemokine receptor binding heterocyclic compounds | GENZYME CORPORATION | 2003-01-23 | — | — | US | disclosed |
| US-6495699-B2 | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | AGOURON PHARMACEUTICALS INC. | 2002-12-17 | — | — | US | disclosed |
| WO-2002022600-A2 | CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS | ANORMED INC. (CA) | 2002-03-21 | — | — | WO | disclosed |
| US-20020019429-A1 | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use | BENDER STEVEN L (US) | 2002-02-14 | — | — | US | disclosed |
| US-6306892-B1 | ENZYME INHIBITORS HETEROCYCLIC AMIDES | AGOURON PHARMACEUTICALS, INC. | 2001-10-23 | — | — | US | disclosed |
| US-6174915-B1 | FOR TREATING MAMMALIAN DISEASE CONDITION MEDIATED BY METALLOPROTEINASE ACTIVITY | AGOURON PHARMACEUTICALS, INC. | 2001-01-16 | — | — | US | disclosed |
| US-6008243-A | AN ENZYME INHIBITOR FOR PREVENTING THE DEGRADATION AND REMODELING OF CONNECTIVE TISSUES | AGOURON PHARMACEUTICALS, INC. (US) | 1999-12-28 | — | — | US | disclosed |
| US-5773428-A | BONE DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0807114-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023791-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210111355-A1 | Tetradentate Platinum And Palladium Complex Emitters Containing Phenyl-Pyrazole And Its Analogues | PDCD1, PDCD11, TYMP | AKT1 3904/4885AKT2 3876/4885RAB9A 1375/4885 |
| US-10836785-B2 | Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues | PAICS, DNTT, PNPO | AKT1 4737/4885AKT2 4773/4885RAB9A 3727/4885 |
| US-20190013485-A1 | Tetradentate Platinum And Palladium Complex Emitters Containing Phenyl-Pyrazole And Its Analogues | PDCD1, PDCD11, HPRT1 | AKT1 3916/4885AKT2 3910/4885RAB9A 1427/4885 |
| US-20230115701-A1 | TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES | PAICS, DNTT, PNPO | AKT1 4737/4885AKT2 4773/4885RAB9A 3727/4885 |
| US-20030018046-A1 | Chemokine receptor binding heterocyclic compounds | CXCR3, ACKR3, CCR2 | AKT1 600/4885AKT2 1377/4885RAB9A 1243/4885 |
| US-20240268216-A1 | TETRADENTATE PLATINUM AND PALLADIUM COMPLEX EMITTERS CONTAINING PHENYL-PYRAZOLE AND ITS ANALOGUES | PDCD1, PDCD11, TYMP | AKT1 3904/4885AKT2 3876/4885RAB9A 1375/4885 |
| US-11930698-B2 | Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues | PDCD1, PDCD11, TYMP | AKT1 3904/4885AKT2 3876/4885RAB9A 1375/4885 |
| US-20020019429-A1 | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use | MMP9, MMP2, MMP3 | AKT1 1740/4885AKT2 1202/4885RAB9A 1037/4885 |
| US-10937976-B2 | Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues | PDCD1, PDCD11, TYMP | AKT1 3904/4885AKT2 3876/4885RAB9A 1375/4885 |
| US-20210024559-A1 | TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES | PAICS, DNTT, PNPO | AKT1 4737/4885AKT2 4773/4885RAB9A 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.