Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL5694233

O=S(=O)(O)C(F)(F)F.c1ccc(-c2c[nH]cn2)cc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.39
HPGD P15428 2/20 0.35
TP53 P04637 2/20 0.35
RAB9A P51151 2/20 0.35
LMNA P02545 2/20 0.35
POLB P06746 2/20 0.35
MEN1 O00255 1/20 0.35
S1PR4 O95977 1/20 0.35
S1PR1 P21453 1/20 0.35
SDHB P21912 1/20 0.35
MAPK1 P28482 1/20 0.35
STAT3 P40763 1/20 0.35
STAT1 P42224 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TLR9 Q9NR96 1/20 0.35
CYP1A2 P05177 2/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL5694238 0.84 CHRNA7 (0.44) HPGDTP53LMNACYP1A2KDM4E
SCHEMBL37563 0.81 KMT2A (0.42) RAB9APOLBMEN1KMT2ACYP1A2
Hydrochloric Acid SCHEMBL11060859 0.79 KMT2A (0.41) RAB9APOLBMEN1KMT2ACYP1A2
Bromide SCHEMBL28947954 0.79 KMT2A (0.41) RAB9APOLBMEN1KMT2ACYP1A2
SCHEMBL4063789 0.77 AKT1 (0.43) RAB9ALMNAPOLBMEN1KMT2A
Succinic Acid SCHEMBL29123713 0.76 FFAR1 (0.43) HPGDTP53RAB9ALMNAHSD17B10
Biphenyl SCHEMBL1050411 0.75 PTPN1 (0.58) PTPN1MEN1MAPK1HTTKMT2A
Trifluoromethanesulfonic Acid SCHEMBL2391326 0.74 CYP2A6 (0.47) PTPN1RAB9ALMNAPOLBCYP1A2
SCHEMBL6197482 0.73 LMNA (0.41) HPGDLMNAPOLBMEN1HTT
Biphenyl SCHEMBL5410059 0.73 PTPN1 (0.56) PTPN1MEN1MAPK1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658396-A1 BELT REACTOR MANUFACTURING PROCESS FOR OLIGOMER SYNTHESIS Arrowhead Pharmaceuticals, Inc. (US) 2025-12-10 EP claimed
WO-2024163644-A1 BELT REACTOR MANUFACTURING PROCESS FOR OLIGOMER SYNTHESIS Arrowhead Pharmaceuticals, Inc. (US) 2024-08-08 WO claimed
EP-4658396-A1 BELT REACTOR MANUFACTURING PROCESS FOR OLIGOMER SYNTHESIS Arrowhead Pharmaceuticals, Inc. (US) 2025-12-10 EP disclosed
EP-4547683-A2 CYCLIC-DISULFIDE MODIFIED PHOSPHATE BASED OLIGONUCLEOTIDE PRODRUGS Alnylam Pharmaceuticals, Inc. (US) 2025-05-07 EP disclosed
US-20240343746-A1 CYCLIC-DISULFIDE MODIFIED PHOSPHATE BASED OLIGONUCLEOTIDE PRODRUGS BANK OF AMERICA, N.A. 2024-10-17 US disclosed
WO-2024163644-A1 BELT REACTOR MANUFACTURING PROCESS FOR OLIGOMER SYNTHESIS Arrowhead Pharmaceuticals, Inc. (US) 2024-08-08 WO disclosed
WO-2024006999-A2 CYCLIC-DISULFIDE MODIFIED PHOSPHATE BASED OLIGONUCLEOTIDE PRODRUGS ALNYLAM PHARMACEUTICALS, INC. (US) 2024-01-04 WO disclosed
EP-4271696-A2 CYCLIC-DISULFIDE MODIFIED PHOSPHATE BASED OLIGONUCLEOTIDE PRODRUGS Alnylam Pharmaceuticals, Inc. (US) 2023-11-08 EP disclosed
WO-2022147214-A2 CYCLIC-DISULFIDE MODIFIED PHOSPHATE BASED OLIGONUCLEOTIDE PRODRUGS ALNYLAM PHARMACEUTICALS, INC. (US) 2022-07-07 WO disclosed
US-20060167241-A1 Method for synthesizing cyclic bisdinucleoside MITSUI CHEMICALS, INC. (JP) 2006-07-27 US disclosed
EP-1645561-A1 METHOD OF SYNTHESIZING CYCLIC BISDINUCLEOSIDE Mitsui Chemicals, Inc. (JP) 2006-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343746-A1 CYCLIC-DISULFIDE MODIFIED PHOSPHATE BASED OLIGONUCLEOTIDE PRODRUGS RNGTT, TYMP, DCTPP1 PTPN1 644/4885HPGD 2096/4885TP53 1073/4885
US-20060167241-A1 Method for synthesizing cyclic bisdinucleoside NSUN2, POLR2H, POLB PTPN1 4638/4885HPGD 1744/4885TP53 2208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.