SCHEMBL291241

SCHEMBL291241

CCC[CH]N(CCCC)CCCC

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.33
ALDH1A1 P00352 3/20 0.33
DNM1 Q05193 3/20 0.32
LMNA P02545 1/20 0.32
ALDH2 P05091 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405763 0.90 DNM1 (0.46) TSHRDNM1CA12CA1CA9
SCHEMBL4395764 0.90 DNM1 (0.46) TSHRDNM1CA12CA1CA9
SCHEMBL3251807 0.90 DNM1 (0.46) TSHRDNM1CA12CA1CA9
SCHEMBL4398444 0.90 DNM1 (0.46) TSHRDNM1CA12CA1CA9
SCHEMBL3027388 0.89 TSHR (0.39) TSHRALDH1A1DNM1LMNAALDH2
SCHEMBL1405684 0.86 TSHR (0.40) TSHRALDH1A1DNM1THRB
SCHEMBL5958083 0.84 TSHR (0.44) TSHRDNM1LMNATHRB
SCHEMBL317337 0.84 TSHR (0.44) TSHRDNM1LMNATHRB
SCHEMBL1448478 0.82 TSHR (0.33) TSHRALDH1A1
SCHEMBL11791586 0.82 ALDH1A1 (0.39) TSHRALDH1A1LMNAALDH2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101312973-B Indolizine derivatives, process for their preparation and pharmaceutical compositions containing them SANOFI-AVENTIS (FR) 2011-12-28 CN claimed
EP-1647555-B1 THE C-GLYCOSYLISOFLAVONES HAVING ALKYLAMINOALKOXYL SUBSTITUENT, THE PREPARATION AND THE USE OF THE SAME INST RADIATION MED AMMS PLA (CN) 2011-04-20 EP claimed
US-7727965-B2 C-glycosylisoflavones having alkylaminoalkoxyl substituent, preparation and use of the same HAINAN YANGPU NEW & SPECIAL MEDICINE CO., LTD. (CN) 2010-06-01 US claimed
US-20080293642-A1 C-Glycosylisoflavones Having Alkylaminoalkoxyl Substituent, Preparation and Use of the Same INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) 2008-11-27 US claimed
CN-101312973-A Indolizine derivatives, process for their preparation and pharmaceutical compositions containing them SANOFI AVENTIS (FR) 2008-11-26 CN claimed
EP-1647555-A1 THE C-GLYCOSYLISOFLAVONES HAVING ALKYLAMINOALKOXYL SUBSTITUENT, THE PREPARATION AND THE USE OF THE SAME Institute of Radiation Medicine Academy of Military Medical Sciences of the Pla (CN) 2006-04-19 EP claimed
US-6111045-A YIELDS A VULCANIZED RUBBER SHOWING IMPROVEMENTS IN HEAT BUILD-UP, TENSILE STRENGTH, ABRASION RESISTANCE AND PROCESSABILITY NIPPON ZEON CO. LTD. (JP) 2000-08-29 US claimed
EP-0433805-A1 N-Substituted 3-cyano-4-phenyl-pyrroles BAYER AG (DE) 1991-06-26 EP claimed
US-4914122-A CONTROLLING PLANT DISEASES BAYER AKTIENGESELLSCHAFT (DE) 1990-04-03 US claimed
EP-0327977-A1 1-Aminomethyl-3-(2,4-difluor-3-chlorphenyl)-4-cyanopyrroles BAYER AG (DE) 1989-08-16 EP claimed
US-20240182810-A1 LUBRICANT OIL COMPOSITION IDEMITSU KOSAN CO.,LTD. (JP) 2024-06-06 US disclosed
US-20240150670-A1 LUBRICATING OIL ADDITIVE COMPOSITION AND LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO.,LTD. (JP) 2024-05-09 US disclosed
EP-4317373-A1 LUBRICANT OIL COMPOSITION Idemitsu Kosan Co.,Ltd. (JP) 2024-02-07 EP disclosed
EP-4317386-A1 LUBRICATING OIL ADDITIVE COMPOSITION AND LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2024-02-07 EP disclosed
EP-4317378-A1 LUBRICATING OIL COMPOSITION Idemitsu Kosan Co.,Ltd. (JP) 2024-02-07 EP disclosed
US-4720493-A Thienylthiazole compounds YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1988-01-19 US disclosed
EP-0183191-A1 Thienylthiazole compounds Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1986-06-04 EP disclosed
EP-0055728-A4 HYDROPHILIC INTERPOLYMERS OF ACRYLIC ACID AND AN ACRYLATE. GOODRICH CO B F (US) 1982-08-11 EP disclosed
EP-0055728-A1 HYDROPHILIC INTERPOLYMERS OF ACRYLIC ACID AND AN ACRYLATE The B.F. GOODRICH Company (US) 1982-07-14 EP disclosed
WO-1982000147-A1 HYDROPHILIC INTERPOLYMERS OF ACRYLIC ACID AND AN ACRYLATE GOODRICH CO B F (US) 1982-01-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293642-A1 C-Glycosylisoflavones Having Alkylaminoalkoxyl Substituent, Preparation and Use of the Same UGCG, PIGO, GPI TSHR 4040/4885ALDH1A1 263/4885DNM1 4047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.