Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124143 | 1.00 | MAPT (0.39) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL29124148 | 0.88 | ALDH1A1 (0.38) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL29124147 | 0.88 | ALDH1A1 (0.38) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL25785186 | 0.82 | HPGD (0.43) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL18689925 | 0.82 | PRMT5 (0.46) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL31279449 | 0.82 | PRMT5 (0.46) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8486518 | 0.79 | NR1H2 (0.43) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL851066 | 0.79 | NR1H2 (0.43) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1733959 | 0.79 | HPGD (0.48) | MAPTHPGDGPR119RECQLEPHX1 | |
| SCHEMBL24826714 | 0.77 | RECQL (0.41) | MAPTALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229289-A | Preparation and application of EGFR inhibitor with macrocyclic structure | 药雅科技(上海)有限公司 | 2023-12-15 | — | — | CN | disclosed |