Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124148 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL29124143 | 0.88 | MAPT (0.39) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL29124139 | 0.88 | MAPT (0.39) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL21777184 | 0.83 | PRMT5 (0.47) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL21767763 | 0.83 | PRMT5 (0.47) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL21767761 | 0.83 | PRMT5 (0.47) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL24826714 | 0.82 | RECQL (0.41) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL25785186 | 0.80 | HPGD (0.43) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL31063148 | 0.76 | PRMT5 (0.43) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL31063417 | 0.76 | PRMT5 (0.43) | ALDH1A1MEN1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229289-A | Preparation and application of EGFR inhibitor with macrocyclic structure | 药雅科技(上海)有限公司 | 2023-12-15 | — | — | CN | disclosed |