SCHEMBL29124508

SCHEMBL29124508

Cc1cccnc1NC(=O)c1ccc2ccccc2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 10/20 0.63
NPC1 O15118 8/20 0.63
ALDH1A1 P00352 4/20 0.60
TP53 P04637 2/20 0.60
HPGD P15428 2/20 0.60
HSD17B10 Q99714 1/20 0.60
L3MBTL1 Q9Y468 2/20 0.58
KMT2A Q03164 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.56
MAPT P10636 1/20 0.56
KDM4E B2RXH2 3/20 0.56
MEN1 O00255 1/20 0.54
LMNA P02545 1/20 0.53
GAA P10253 1/20 0.53
ALOX15 P16050 1/20 0.53
ALOX12 P18054 1/20 0.53
DHODH Q02127 1/20 0.53
HTT P42858 1/20 0.52
ATM Q13315 1/20 0.52
DEGS1 O15121 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30594478 1.00 RAB9A (0.63) RAB9ANPC1ALDH1A1TP53HPGD
SCHEMBL7345835 0.87 ALDH1A1 (0.58) RAB9ANPC1ALDH1A1TP53HPGD
Hydrochloric Acid SCHEMBL7373965 0.86 ALDH1A1 (0.57) RAB9ANPC1ALDH1A1TP53HPGD
SCHEMBL7532358 0.82 KMT2A (0.68) RAB9ANPC1ALDH1A1TP53HPGD
SCHEMBL7345841 0.82 ALDH1A1 (0.53) RAB9ANPC1ALDH1A1TP53HPGD
Hydrochloric Acid SCHEMBL7373968 0.81 ALDH1A1 (0.53) RAB9ANPC1ALDH1A1TP53HPGD
Trifluoroacetic Acid SCHEMBL7844475 0.80 PLAU (0.52) RAB9ANPC1ALDH1A1TP53HPGD
SCHEMBL8555646 0.80 KMT2A (0.63) RAB9ANPC1ALDH1A1TP53HPGD
SCHEMBL21870332 0.78 NPC1 (1.00) RAB9ANPC1ALDH1A1TP53HPGD
SCHEMBL8554315 0.78 RAB9A (0.58) RAB9ANPC1ALDH1A1TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861108-B Method for synthesizing carbamate compound by esterification reaction of amide and alcohol at room temperature 内蒙古师范大学 2023-11-10 CN disclosed
CN-114014803-B Method for synthesizing urea compound by amidation reaction of amide and amine at room temperature 内蒙古师范大学 2023-11-10 CN disclosed