Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | PLAU | P00749 | 13/20 | 0.56 |
| ▸ | PLG | P00747 | 8/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.56 |
| ▸ | F2 | P00734 | 6/20 | 0.56 |
| ▸ | PLAT | P00750 | 6/20 | 0.56 |
| ▸ | KLK1 | P06870 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7373965 | 0.99 | ALDH1A1 (0.57) | ALDH1A1TP53HPGDHSD17B10RAB9A | |
| Trifluoroacetic Acid SCHEMBL7844475 | 0.92 | PLAU (0.52) | ALDH1A1TP53HPGDHSD17B10RAB9A | |
| SCHEMBL30594478 | 0.87 | RAB9A (0.63) | ALDH1A1TP53HPGDHSD17B10RAB9A | |
| SCHEMBL29124508 | 0.87 | RAB9A (0.63) | ALDH1A1TP53HPGDHSD17B10RAB9A | |
| SCHEMBL7345841 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TP53HPGDHSD17B10RAB9A | |
| Hydrochloric Acid SCHEMBL7373968 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TP53HPGDHSD17B10RAB9A | |
| SCHEMBL8555646 | 0.76 | KMT2A (0.63) | ALDH1A1TP53HPGDHSD17B10RAB9A | |
| SCHEMBL7337891 | 0.76 | PABPC1 (0.65) | RAB9APLAUPLGKLKB1PRSS1 | |
| SCHEMBL7532358 | 0.75 | KMT2A (0.68) | ALDH1A1TP53HPGDHSD17B10RAB9A | |
| SCHEMBL7341806 | 0.74 | SIRT2 (0.59) | PLAUPLGKLKB1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010049374-A1 | Urokinase inhibitors | STEELE ANDREW W (US) | 2001-12-06 | — | — | US | disclosed |
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |
| US-6258822-B1 | ENZYME INHIBITORS OF NAPHTHALENE AMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010049374-A1 | Urokinase inhibitors | SERPINE1, PLAU, SERPINB1 | ALDH1A1 920/4885TP53 3803/4885HPGD 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.