SCHEMBL2912453

SCHEMBL2912453

Cc1ccc(NC(=O)c2cc(C(=O)Nc3ccc(C)cc3)cc(C(=O)Nc3ccc(C)cc3)c2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 11/20 0.80
NPC1 O15118 10/20 0.80
SMN1; SMN2 Q16637 6/20 0.71
MAPT P10636 1/20 0.71
TP53 P04637 3/20 0.60
KDM4E B2RXH2 1/20 0.60
TSHR P16473 1/20 0.60
NFKB1 P19838 1/20 0.60
NFKB2 Q00653 1/20 0.60
RELA Q04206 1/20 0.60
TDP1 Q9NUW8 1/20 0.59
TOP1 P11387 1/20 0.59
TOP2A P11388 1/20 0.59
TOP2B Q02880 1/20 0.59
LMNA P02545 1/20 0.58
HPGD P15428 1/20 0.58
THRB P10828 1/20 0.58
POLB P06746 1/20 0.57
NQO2 P16083 1/20 0.57
SNCA P37840 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15214321 0.89 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTTP53
SCHEMBL27181403 0.89 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTTP53
SCHEMBL12310125 0.89 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTTP53
SCHEMBL14580374 0.89 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTTP53
SCHEMBL822378 0.89 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTTP53
SCHEMBL14008035 0.88 NQO2 (0.76) RAB9ANPC1SMN1; SMN2MAPTTP53
SCHEMBL17327564 0.87 RAB9A (0.67) RAB9ANPC1SMN1; SMN2MAPTTP53
SCHEMBL18027719 0.87 TOP1 (0.82) RAB9ANPC1SMN1; SMN2MAPTTP53
SCHEMBL13065997 0.86 NPC1 (0.61) RAB9ANPC1SMN1; SMN2MAPTTP53
SCHEMBL6881442 0.84 NPC1 (0.73) RAB9ANPC1SMN1; SMN2MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732198-B2 Mono- and multi-layer blown films BASF SE (DE) 2017-08-15 US disclosed
US-20170081486-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2017-03-23 US disclosed
WO-2016190105-A1 POLYIMIDE FILM, METHOD FOR PRODUCING POLYIMIDE FILM, FLEXIBLE PRINTED BOARD, SUBSTRATE FOR FLEXIBLE DISPLAYS, FRONT PLATE FOR FLEXIBLE DISPLAYS, LED LIGHTING DEVICE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE コニカミノルタ株式会社 2016-12-01 WO disclosed
US-20160136871-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2016-05-19 US disclosed
US-9278487-B2 Mono-and multi-layer blown films BASF SE (DE) 2016-03-08 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-8496848-B2 Films and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-30 US disclosed
US-8496848-B2 Films and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-30 US disclosed
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20130161875-A1 MONO-AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2013-06-27 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed
EP-2026965-B1 MONO- AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2010-09-01 EP disclosed
US-20090208718-A1 Mono-and multi-layer blown films CIBA CORP. 2009-08-20 US disclosed
US-20090104378-A1 Optical Film and Method for Manufacturing the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-23 US disclosed
US-20090104378-A1 Optical Film and Method for Manufacturing the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-23 US disclosed
US-20090072194-A1 Films and Processes for Producing the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-19 US disclosed
US-20090072194-A1 Films and Processes for Producing the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-19 US disclosed