SCHEMBL29124599

SCHEMBL29124599

CCOC(=O)CC(C)C(CCCC(=O)O)(C(=O)O)C(C)CC(=O)OCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
GAA P10253 2/20 0.36
MGAM O43451 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
TSHR P16473 6/20 0.34
AKR1B1 P15121 1/20 0.33
NR1I2 O75469 1/20 0.33
PGR P06401 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
PTGS2 P35354 1/20 0.33
PDE4D Q08499 1/20 0.33
ALDH1A1 P00352 4/20 0.33
GPR84 Q9NQS5 7/20 0.32
PPARG P37231 6/20 0.32
PPARD Q03181 6/20 0.32
PPARA Q07869 6/20 0.32
HDAC11 Q96DB2 5/20 0.32
TLR2 O60603 2/20 0.32
TDP1 Q9NUW8 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29124822 0.82 GAA (0.38) CYP1A2GAAMGAMSIMGAM2
SCHEMBL29124622 0.82 GAA (0.38) CYP1A2GAAMGAMSIMGAM2
SCHEMBL4394093 0.77 ALDH1A1 (0.35) CYP1A2TSHRAKR1B1ALDH1A1GPR84
SCHEMBL29124620 0.76 GAA (0.41) CYP1A2GAAMGAMSIMGAM2
SCHEMBL1302163 0.76 AKR1B1 (0.36) CYP1A2TSHRAKR1B1ALDH1A1GPR84
SCHEMBL7866598 0.76 AKR1B1 (0.45) TSHRAKR1B1ALDH1A1GPR84PPARG
Adipic Acid SCHEMBL29124681 0.75 AKR1B1 (0.43) CYP1A2TSHRAKR1B1ALDH1A1GPR84
SCHEMBL3765877 0.75 LMNA (0.36) CYP1A2TSHRAKR1B1ALDH1A1GPR84
SCHEMBL136592 0.74 LMNA (0.42) CYP1A2TSHRAKR1B1ALDH1A1GPR84
SCHEMBL15281992 0.73 FFAR4 (0.53) CYP1A2TSHRAKR1B1ALDH1A1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116917264-A Process for preparing hydroxybutyric acid carboxylic ester 凯托利皮克斯治疗有限责任公司 2023-10-20 CN disclosed