Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL7617176 | 1.00 | LMNA (0.50) | LMNAALKBH5SUCNR1EGLN1SLC22A6 | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL28197574 | 0.91 | SLC22A6 (0.56) | LMNASLC22A6SMN1; SMN2FFAR3MAPT | |
| (R)-3-Hydroxybutanoate SCHEMBL29903959 | 0.91 | — | — | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL2731 | 0.91 | — | — | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL1897117 | 0.91 | SLC22A6 (0.56) | LMNASLC22A6SMN1; SMN2FFAR3MAPT | |
| (R)-3-Hydroxybutanoate SCHEMBL336331 | 0.91 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL60959 | 0.91 | — | — | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL1881926 | 0.91 | SLC22A6 (0.56) | LMNASLC22A6SMN1; SMN2FFAR3MAPT | |
| (R)-3-Hydroxybutanoate SCHEMBL1533862 | 0.91 | SLC22A6 (0.56) | LMNASLC22A6SMN1; SMN2FFAR3MAPT | |
| Adipic Acid SCHEMBL29124686 | 0.90 | LMNA (0.55) | LMNASLC22A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917264-A | Process for preparing hydroxybutyric acid carboxylic ester | 凯托利皮克斯治疗有限责任公司 | 2023-10-20 | — | — | CN | disclosed |