Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124749 | 0.95 | CHKA (0.35) | CHKAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29124848 | 0.89 | MEN1 (0.35) | MAPTMEN1KMT2ABCL2A1CYP3A4 | |
| SCHEMBL30609182 | 0.85 | CHKA (0.47) | CHKAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30609193 | 0.83 | CHKA (0.45) | CHKAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29124843 | 0.76 | SMN1; SMN2 (0.36) | SMN1; SMN2L3MBTL1MAPTHTTMEN1 | |
| SCHEMBL28070643 | 0.73 | MAPT (0.48) | CHKAALDH1A1L3MBTL1MAPTHTT | |
| SCHEMBL4068610 | 0.73 | ADRB1 (0.48) | ALDH1A1RAB9AL3MBTL1MAPTHTT | |
| SCHEMBL29124645 | 0.73 | LMNA (0.41) | ALDH1A1SMN1; SMN2L3MBTL1LMNAPIM2 | |
| SCHEMBL28179046 | 0.72 | CHKA (0.48) | CHKAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29124687 | 0.70 | PIM1 (0.36) | PIM1PIM3PIM2ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |