Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | KDM5A | P29375 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | OGG1 | O15527 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2678949 | 0.82 | MPO (0.80) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL343630 | 0.82 | MPO (0.80) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL28188923 | 0.79 | MPO (0.76) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL30782680 | 0.77 | ALDH1A1 (0.58) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL3539246 | 0.76 | PARP10 (0.48) | CYP3A4BLMPMP22MAPTALDH1A1 | |
| SCHEMBL222973 | 0.76 | MPO (0.64) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL9908251 | 0.76 | MPO (0.64) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL9627168 | 0.76 | MPO (0.64) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL752600 | 0.75 | MPO (0.70) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL11134828 | 0.75 | MPO (0.70) | MPOCYP3A4BLMKDM5AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117582436-A | Iminoacyl hydrazides, compositions containing same and uses thereof | 甫康（上海）健康科技有限责任公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-116836173-B | Iminoacyl hydrazides, compositions containing same and uses thereof | 甫康（上海）健康科技有限责任公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-116836173-A | Iminoacyl hydrazides, compositions containing same and uses thereof | 甫康（上海）健康科技有限责任公司 | 2023-10-03 | — | — | CN | disclosed |