SCHEMBL222973

SCHEMBL222973

NNC(=O)c1ccc(F)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPO P05164 2/20 0.64
CYP3A4 P08684 2/20 0.64
KDM5A P29375 1/20 0.64
BLM P54132 1/20 0.64
GFER P55789 1/20 0.64
PMP22 Q01453 1/20 0.64
HIF1A Q16665 1/20 0.64
MAPT P10636 3/20 0.61
ALDH1A1 P00352 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
KDM4E B2RXH2 2/20 0.61
OGG1 O15527 1/20 0.61
LMNA P02545 1/20 0.61
CYP1A2 P05177 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2A6 P11509 1/20 0.56
CYP2C19 P33261 1/20 0.56
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9908251 1.00 MPO (0.64) MPOCYP3A4KDM5ABLMGFER
Water SCHEMBL8856772 0.98 MPO (0.61) MPOCYP3A4KDM5ABLMGFER
Hydrochloric Acid SCHEMBL5800195 0.98 MPO (0.61) MPOCYP3A4KDM5ABLMGFER
Trifluoroacetic Acid SCHEMBL27664698 0.88 PLOD2 (0.53) MPOCYP3A4KDM5ABLMGFER
SCHEMBL4249220 0.88 PTPN1 (0.73) LMNAMEN1KMT2APTPN1MITF
SCHEMBL16827365 0.88 CA1 (0.59) MPOCYP3A4KDM5ABLMGFER
SCHEMBL343630 0.87 MPO (0.80) MPOCYP3A4KDM5ABLMGFER
SCHEMBL2678949 0.87 MPO (0.80) MPOCYP3A4KDM5ABLMGFER
SCHEMBL28188923 0.85 MPO (0.76) MPOCYP3A4KDM5ABLMGFER
Water SCHEMBL9038134 0.82 ALDH1A1 (0.50) MPOCYP3A4KDM5ABLMGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 795 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977833-A Synthesis and antitumor application of erianin derivative 江苏海洋大学 2025-05-13 CN claimed
CN-118812539-A 5-Aminotriazolopyrimidine derivative and preparation method thereof 苏州大学 2024-10-22 CN claimed
US-20240158658-A1 IODINE REDUCTION FOR REPRODUCIBLE AND HIGH PERFORMANCE PEROVSKITE SOLAR CELLS AND MODULES UNITED STATES DEPARTMENT OF ENERGY 2024-05-16 US claimed
CN-117630077-A Based on 19 Method for detecting protein carbonylation by F nuclear magnetic resonance 中国科学院精密测量科学与技术创新研究院 2024-03-01 CN claimed
CN-117402125-A Preparation method of noo Bo Suan oxadiazole thioester compound, product and application thereof 南京林业大学 2024-01-16 CN claimed
WO-2022177642-A9 IODINE REDUCTION FOR REPRODUCIBLE AND HIGH PERFORMANCE PEROVSKITE SOLAR CELLS AND MODULES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2022-11-03 WO claimed
CN-114685536-B Binuclear cadmium complex with anticancer activity and preparation method and application thereof 中山职业技术学院 2022-09-02 CN claimed
WO-2022177642-A2 IODINE REDUCTION FOR REPRODUCIBLE AND HIGH PERFORMANCE PEROVSKITE SOLAR CELLS AND MODULES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2022-08-25 WO claimed
US-11398630-B2 Method of generating energy from a hydrazide containing anode fuel, and fuel cell IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2022-07-26 US claimed
CN-114773278-A Quinazoline compound and application thereof in antivirus 苏州大学 2022-07-22 CN claimed
CN-105669491-B A kind of acylation method of amine 苏州大学 2017-10-13 CN claimed
US-20160297732-A1 METHOD FOR MANUFACTURING HIGH PURITY GLYCOL BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-13 US claimed
CN-105669491-A Acidylation method of amine 苏州大学 2016-06-15 CN claimed
CN-104177459-A 1,3,4-oxadiazole derivative containing glucosamine fragment as well as synthetic method and use of derivative HUAIHAI INST TECHNOLOGY 2014-12-03 CN claimed
CN-104151371-A N-acetylglucosamine-N'-acylamino thiourea as well as synthesis method and application thereof HUAIHAI INST TECHNOLOGY 2014-11-19 CN claimed
CN-102690258-A Nitrogenous heterocyclic-imide derivative and preparation method and purpose thereof HUBEI BIOPESTICIDE ENGINEERING RES CT 2012-09-26 CN claimed
CN-1161325-C Diacyl hydrazide compounds as insecticide, intermediate for preparing said compounds and their preparing process 江苏省农药研究所 2004-08-11 CN claimed
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2003-06-05 US claimed
WO-2002102301-A2 SUBSTITUTED INDOLE-2-CARBOXYLIC ACID BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF CYTOVIA, INC. (US) 2002-12-27 WO claimed
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2002-09-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 MPO 2665/4885CYP3A4 1159/4885KDM5A 2065/4885
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 MPO 2665/4885CYP3A4 1159/4885KDM5A 2065/4885
US-20160297732-A1 METHOD FOR MANUFACTURING HIGH PURITY GLYCOL BASED COMPOUND GK, GMDS, UGCG MPO 1470/4885CYP3A4 919/4885KDM5A 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.