Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2912562

CCCCCCCCCCCCCCCCCCC(O)C[N+](C)(C)CC(O)CCCCCCCCCCCCCCCCCC.[Cl-]

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 2/20 0.72
PLA2G1B P04054 2/20 0.72
MMP2 P08253 2/20 0.72
ATG4B Q9Y4P1 2/20 0.72
HSP90AA1 P07900 1/20 0.72
RAD52 P43351 1/20 0.67
GPR84 Q9NQS5 8/20 0.55
FFAR1 O14842 2/20 0.53
FFAR4 Q5NUL3 1/20 0.53
NFKB1 P19838 1/20 0.47
FDPS P14324 3/20 0.43
SPHK1 Q9NYA1 1/20 0.43
FAAH O00519 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11215399 1.00 PSMD14 (0.72) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL11875761 1.00 PSMD14 (0.72) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL11227182 1.00 PSMD14 (0.72) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
SCHEMBL8040639 0.98 PSMD14 (0.69) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL45756 0.98 PSMD14 (0.69) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL11527519 0.92 PLA2G1B (0.74) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL11595988 0.92 PLA2G1B (0.74) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL11596806 0.92 PLA2G1B (0.74) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL27937632 0.92 PLA2G1B (0.74) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL28668483 0.92 PLA2G1B (0.74) PSMD14PLA2G1BMMP2ATG4BHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421048-B2 Dual activated microgel LUBRIZOL ADVANCED MATERIALS, INC. (US) 2022-08-23 US disclosed
EP-3635017-B1 DUAL ACTIVATED MICROGEL LUBRIZOL ADVANCED MAT INC (US) 2021-07-07 EP disclosed
US-20200255568-A1 DUAL ACTIVATED MICROGEL LUBRIZOL ADVANCED MATERIALS, INC. (US) 2020-08-13 US disclosed
US-20180265825-A1 LAUNDRY DETERGENT COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. 2018-09-20 US disclosed
EP-3237594-B1 LAUNDRY DETERGENT COMPOSITIONS STABILIZED WITH AN AMPHIPHILIC RHEOLOGY MODIFIER CROSSLINKED WITH AN AMPHIPHILIC CROSSLINKER LUBRIZOL ADVANCED MAT INC (US) 2018-05-16 EP disclosed
US-20170369818-A1 LAUNDRY DETERGENT COMPOSITIONS STABILIZED WITH AN AMPHIPHILIC RHEOLOGY MODIFIER CROSSLINKED WITH AN AMPHIPHILIC CROSSLINKER LUBRIZOL ADVANCED MATERIALS, INC. 2017-12-28 US disclosed
EP-3237593-A1 LAUNDRY DETERGENT COMPOSITIONS Lubrizol Advanced Materials, Inc. (US) 2017-11-01 EP disclosed
EP-3237594-A1 LAUNDRY DETERGENT COMPOSITIONS STABILIZED WITH AN AMPHIPHILIC RHEOLOGY MODIFIER CROSSLINKED WITH AN AMPHIPHILIC CROSSLINKER Lubrizol Advanced Materials, Inc. (US) 2017-11-01 EP disclosed
WO-2016106167-A1 LAUNDRY DETERGENT COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2016-06-30 WO disclosed
WO-2016106168-A1 LAUNDRY DETERGENT COMPOSITIONS STABILIZED WITH AN AMPHIPHILIC RHEOLOGY MODIFIER CROSSLINKED WITH AN AMPHIPHILIC CROSSLINKER LUBRIZOL ADVANCED MATERIALS, INC. (US) 2016-06-30 WO disclosed
EP-0950087-B1 COMPOSITIONS CONTAINING PERFUME GIVAUDAN NEDERLAND SERVICES B (NL) 2010-08-11 EP disclosed
US-6024943-A POLYMER CORES WITH COATINGS QUEST INTERNATIONAL B.V. (NL) 2000-02-15 US disclosed